Motif ID: Mef2b
Z-value: 0.700
Transcription factors associated with Mef2b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mef2b | ENSMUSG00000079033.3 | Mef2b |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mef2b | mm10_v2_chr8_+_70152754_70152781 | 0.05 | 8.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.5 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.0 | 3.8 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.7 | 2.2 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.7 | 3.4 | GO:0015671 | oxygen transport(GO:0015671) |
0.5 | 1.5 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.4 | 1.3 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
0.4 | 1.1 | GO:0060023 | soft palate development(GO:0060023) |
0.4 | 1.8 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
0.3 | 1.9 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.3 | 1.2 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.3 | 1.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
0.3 | 0.8 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
0.2 | 0.7 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.2 | 1.1 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
0.2 | 1.0 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.2 | 1.0 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.2 | 1.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.2 | 2.0 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.2 | 0.7 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.2 | 0.9 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.2 | 2.8 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.2 | 2.9 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.2 | 0.5 | GO:1990481 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481) |
0.1 | 0.4 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.9 | GO:0015879 | carnitine transport(GO:0015879) |
0.1 | 1.1 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.1 | 1.5 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.1 | 0.6 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.1 | 0.3 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
0.1 | 0.8 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.1 | 1.2 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.1 | 0.7 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.1 | 0.8 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.4 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.1 | 0.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 0.8 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 0.1 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.1 | 2.6 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.4 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.0 | 0.6 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 1.0 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 1.9 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
0.0 | 1.9 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.0 | 0.4 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.0 | 0.4 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.6 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.2 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) trophectodermal cell proliferation(GO:0001834) |
0.0 | 0.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 0.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.0 | 0.8 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 0.1 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.0 | 0.5 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.1 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.0 | 0.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 0.3 | GO:0019369 | drug metabolic process(GO:0017144) arachidonic acid metabolic process(GO:0019369) |
0.0 | 0.4 | GO:0007612 | learning(GO:0007612) |
0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
0.0 | 0.4 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.0 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.0 | 0.4 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.1 | GO:1902969 | mitotic DNA replication(GO:1902969) |
0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.0 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 0.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 0.8 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.2 | 3.8 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.1 | 1.1 | GO:0098536 | deuterosome(GO:0098536) |
0.1 | 1.7 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 0.5 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.1 | 0.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.1 | 0.8 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.8 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.1 | 2.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 0.3 | GO:0090537 | CERF complex(GO:0090537) |
0.1 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.1 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.0 | 0.5 | GO:0043194 | axon initial segment(GO:0043194) |
0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.4 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 1.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 1.2 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 2.6 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 1.0 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.8 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.6 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.5 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 1.0 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.6 | GO:0014704 | intercalated disc(GO:0014704) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.4 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.7 | 2.2 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.6 | 3.8 | GO:0035240 | dopamine binding(GO:0035240) |
0.5 | 1.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.4 | 2.9 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.3 | 0.9 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.2 | 1.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.2 | 0.7 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.2 | 0.8 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.2 | 0.5 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.2 | 0.5 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.1 | 1.0 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 2.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 0.8 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.1 | 0.5 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 1.2 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.1 | 0.3 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
0.1 | 1.9 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 0.7 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 1.8 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.1 | 0.2 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.1 | 0.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.3 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 1.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.5 | GO:0017046 | peptide hormone binding(GO:0017046) |
0.0 | 1.0 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 1.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.4 | GO:0035925 | translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.1 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
0.0 | 2.6 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.8 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 0.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.1 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.0 | 0.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 0.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.0 | 0.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 3.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 1.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.0 | 0.6 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 0.8 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |