Motif ID: Mef2b

Z-value: 0.700


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_701527810.058.2e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 6.465 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_-_172043466 3.972 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr7_-_142899985 3.832 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr7_-_103843154 3.407 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr18_+_60963517 2.780 ENSMUST00000115295.2
ENSMUST00000039904.6
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chrY_-_1286563 2.596 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr5_+_24985840 2.528 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_+_31089471 2.243 ENSMUST00000036631.7
ENSMUST00000170204.1
 Dusp26

dual specificity phosphatase 26 (putative)

chr13_+_5861489 2.056 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr1_+_187609028 1.923 ENSMUST00000110939.1
 Esrrg
estrogen-related receptor gamma
chr5_-_128953303 1.891 ENSMUST00000111346.1
 Rimbp2
RIMS binding protein 2
chr12_-_111672290 1.850 ENSMUST00000001304.7
 Ckb
creatine kinase, brain
chr6_+_137410721 1.761 ENSMUST00000167002.1
 Ptpro
protein tyrosine phosphatase, receptor type, O
chr3_+_146852359 1.696 ENSMUST00000038090.5
ENSMUST00000170055.1
 Ttll7

tubulin tyrosine ligase-like family, member 7

chr18_+_50030977 1.635 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr9_-_110742577 1.516 ENSMUST00000006005.7
 Pth1r
parathyroid hormone 1 receptor
chr9_-_110654161 1.501 ENSMUST00000133191.1
ENSMUST00000167320.1
 Nbeal2

neurobeachin-like 2

chr3_+_96596628 1.327 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr18_-_25753852 1.279 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr1_-_12991109 1.247 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 6.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 3.8 GO:0042414 epinephrine metabolic process(GO:0042414)
0.7 3.4 GO:0015671 oxygen transport(GO:0015671)
0.2 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 2.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.7 2.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 2.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.3 1.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 1.9 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.4 1.8 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 1.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 1.5 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 1.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.4 1.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.3 1.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.4 1.1 GO:0060023 soft palate development(GO:0060023)
0.3 1.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 3.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 2.6 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 2.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.1 GO:0098536 deuterosome(GO:0098536)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.2 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0036126 sperm flagellum(GO:0036126)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.1 0.5 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.8 GO:0035240 dopamine binding(GO:0035240)
0.9 3.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 3.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4 2.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.7 2.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.5 1.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 0.9 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 0.8 GO:1904288 BAT3 complex binding(GO:1904288)