Motif ID: Zbtb7c
Z-value: 0.872
Transcription factors associated with Zbtb7c:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zbtb7c | ENSMUSG00000044646.8 | Zbtb7c |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb7c | mm10_v2_chr18_+_75820174_75820210 | -0.55 | 6.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.3 | GO:0090467 | lysine transport(GO:0015819) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023) |
0.5 | 2.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.3 | 1.4 | GO:2000054 | negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054) |
0.3 | 1.6 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
0.3 | 1.0 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.3 | 0.9 | GO:1904742 | protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742) |
0.3 | 0.9 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) |
0.3 | 0.9 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
0.3 | 0.8 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) |
0.2 | 1.4 | GO:0051013 | microtubule severing(GO:0051013) |
0.2 | 1.6 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
0.2 | 2.7 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.2 | 0.2 | GO:0007521 | muscle cell fate determination(GO:0007521) |
0.2 | 1.7 | GO:0043383 | negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060) |
0.2 | 2.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.2 | 0.6 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
0.2 | 1.1 | GO:0007296 | vitellogenesis(GO:0007296) |
0.2 | 0.8 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
0.1 | 0.4 | GO:0072718 | response to cisplatin(GO:0072718) |
0.1 | 0.5 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.1 | 0.8 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 1.6 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.1 | 1.4 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
0.1 | 1.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.6 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.1 | 1.1 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.1 | 1.9 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.1 | 0.4 | GO:0044340 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
0.1 | 1.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.1 | 0.3 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
0.1 | 0.6 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.1 | 0.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.1 | 0.4 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.1 | 0.4 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
0.1 | 0.6 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.1 | 0.5 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.5 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.0 | 0.6 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.5 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 2.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 1.0 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
0.0 | 1.0 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 2.8 | GO:0015807 | L-amino acid transport(GO:0015807) |
0.0 | 0.3 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
0.0 | 0.2 | GO:0040031 | snRNA modification(GO:0040031) |
0.0 | 1.5 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
0.0 | 0.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.8 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
0.0 | 0.6 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 1.7 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 2.7 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.0 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.2 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
0.0 | 0.5 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 0.4 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.0 | 0.1 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.7 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
0.5 | 2.7 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.2 | 1.5 | GO:0008091 | spectrin(GO:0008091) |
0.2 | 0.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.2 | 1.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.2 | 1.6 | GO:0045298 | tubulin complex(GO:0045298) |
0.1 | 0.4 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.1 | 0.4 | GO:0097651 | phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
0.1 | 1.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.1 | 3.0 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 0.6 | GO:0061574 | ASAP complex(GO:0061574) |
0.1 | 2.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.6 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.1 | 0.8 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 1.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 1.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 1.0 | GO:0030118 | clathrin coat(GO:0030118) |
0.0 | 0.9 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.4 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 1.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.3 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.3 | 2.7 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.3 | 1.0 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.2 | 0.9 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.6 | GO:2001069 | glycogen binding(GO:2001069) |
0.1 | 0.8 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
0.1 | 1.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 1.5 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.1 | 3.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 2.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.8 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
0.1 | 0.8 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.1 | 0.8 | GO:0000182 | rDNA binding(GO:0000182) |
0.1 | 2.7 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.1 | 1.4 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.1 | 1.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 2.8 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 0.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.1 | 1.5 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.1 | 0.2 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
0.0 | 0.3 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 0.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.5 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.0 | 0.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.5 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 2.3 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 0.5 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 1.6 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
0.0 | 0.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 4.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 1.8 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 0.3 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.0 | 1.4 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.2 | GO:0030553 | cGMP binding(GO:0030553) |
0.0 | 0.7 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.4 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |