Motif ID: Zbtb7c

Z-value: 0.872


Transcription factors associated with Zbtb7c:

Gene SymbolEntrez IDGene Name
Zbtb7c ENSMUSG00000044646.8 Zbtb7c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7cmm10_v2_chr18_+_75820174_75820210-0.556.2e-03Click!


Activity profile for motif Zbtb7c.

activity profile for motif Zbtb7c


Sorted Z-values histogram for motif Zbtb7c

Sorted Z-values for motif Zbtb7c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7c

PNG image of the network

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Top targets:


Showing 1 to 20 of 140 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_40862379 3.302 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
 Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr4_-_22488296 2.699 ENSMUST00000178174.1
 Pou3f2
POU domain, class 3, transcription factor 2
chr11_-_26210553 2.615 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr18_+_32938955 2.576 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr7_-_19310035 2.208 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B
chr2_-_29253001 2.178 ENSMUST00000071201.4
 Ntng2
netrin G2
chr1_-_153332724 2.045 ENSMUST00000027752.8
 Lamc1
laminin, gamma 1
chr15_-_100599864 1.688 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr16_+_11984581 1.682 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr4_-_120287349 1.658 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr9_+_67840386 1.617 ENSMUST00000077879.5
 Vps13c
vacuolar protein sorting 13C (yeast)
chr15_+_78899755 1.566 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
 Sh3bp1


SH3-domain binding protein 1


chr8_-_11312731 1.556 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr3_+_107036156 1.513 ENSMUST00000052718.3
 Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr9_+_100643755 1.508 ENSMUST00000133388.1
 Stag1
stromal antigen 1
chr12_-_76709997 1.472 ENSMUST00000166101.1
 Sptb
spectrin beta, erythrocytic
chr5_-_148928619 1.416 ENSMUST00000149169.1
ENSMUST00000047257.8
 Katnal1

katanin p60 subunit A-like 1

chr9_+_31280525 1.415 ENSMUST00000117389.1
 Prdm10
PR domain containing 10
chr11_+_108921648 1.397 ENSMUST00000144511.1
 Axin2
axin2
chr11_+_53519920 1.362 ENSMUST00000147912.1
 Sept8
septin 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.3 GO:0090467 lysine transport(GO:0015819) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 2.8 GO:0015807 L-amino acid transport(GO:0015807)
0.2 2.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 2.7 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.2 2.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 2.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.5 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.9 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 1.7 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.3 1.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 1.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 1.5 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.3 1.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 1.4 GO:0051013 microtubule severing(GO:0051013)
0.1 1.4 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.1 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.7 2.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.5 2.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.6 GO:0045298 tubulin complex(GO:0045298)
0.2 1.5 GO:0008091 spectrin(GO:0008091)
0.0 1.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.0 GO:0030118 clathrin coat(GO:0030118)
0.2 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.4 GO:0045098 type III intermediate filament(GO:0045098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.5 3.3 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 2.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 2.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 2.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.3 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.8 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.6 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 1.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)