Motif ID: Zfhx3
Z-value: 0.806
Transcription factors associated with Zfhx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zfhx3 | ENSMUSG00000038872.8 | Zfhx3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zfhx3 | mm10_v2_chr8_+_108714644_108714644 | -0.19 | 3.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.4 | 1.8 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.3 | 1.0 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.3 | 1.0 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
0.3 | 0.9 | GO:0003195 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
0.1 | 0.6 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.8 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.1 | 2.1 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 0.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 5.0 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.1 | 2.2 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.1 | 0.4 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 1.8 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 0.3 | GO:1900272 | negative regulation of long-term synaptic potentiation(GO:1900272) |
0.1 | 0.4 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.1 | 1.4 | GO:0007097 | nuclear migration(GO:0007097) |
0.1 | 0.5 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 0.8 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.1 | 0.6 | GO:0080009 | mRNA methylation(GO:0080009) |
0.1 | 0.3 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 0.3 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.0 | 0.2 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.0 | 0.4 | GO:2000780 | negative regulation of double-strand break repair(GO:2000780) |
0.0 | 1.0 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.3 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.0 | 0.2 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.0 | 1.1 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
0.0 | 1.7 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.1 | GO:0040031 | snRNA modification(GO:0040031) |
0.0 | 0.5 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
0.0 | 2.3 | GO:0051291 | protein heterooligomerization(GO:0051291) |
0.0 | 0.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.0 | 0.5 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 1.4 | GO:0051592 | response to calcium ion(GO:0051592) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.6 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.6 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
0.1 | 1.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.4 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
0.1 | 5.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 0.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.0 | 0.4 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.0 | 0.9 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 1.0 | GO:0001741 | XY body(GO:0001741) |
0.0 | 1.7 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 1.0 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 1.4 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 0.5 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.3 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
0.3 | 0.9 | GO:0035939 | microsatellite binding(GO:0035939) |
0.2 | 1.0 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
0.1 | 2.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 0.6 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 1.0 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.1 | 1.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.4 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 0.7 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
0.0 | 1.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 1.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.0 | 0.5 | GO:0070513 | death domain binding(GO:0070513) |
0.0 | 0.8 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.3 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
0.0 | 0.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 5.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |