Motif ID: Foxp1_Foxj2

Z-value: 0.787

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.711.6e-04Click!
Foxp1mm10_v2_chr6_-_99028874_990289420.482.0e-02Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22439719 3.291 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr4_-_151108244 2.415 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr16_-_43979050 2.388 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr8_-_84773381 2.280 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr16_-_22439570 2.130 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr6_-_39725193 1.897 ENSMUST00000101497.3
 Braf
Braf transforming gene
chr5_+_122643878 1.773 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr8_+_66386292 1.611 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr16_-_34263179 1.579 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chrY_+_1010543 1.514 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr4_-_87806296 1.326 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr6_+_8520008 1.322 ENSMUST00000162567.1
ENSMUST00000161217.1
 Glcci1

glucocorticoid induced transcript 1

chr3_+_5218589 1.303 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr16_+_42907563 1.276 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr17_+_35076902 1.271 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr16_+_43508118 1.251 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr3_+_5218516 1.242 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr16_-_34262945 1.221 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr7_+_19359740 1.193 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr7_+_141476374 1.182 ENSMUST00000117634.1
 Tspan4
tetraspanin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 303 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 5.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 3.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 2.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 2.6 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 2.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 2.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.3 GO:0042572 retinol metabolic process(GO:0042572)
0.2 2.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 2.1 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.2 2.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of fibroblast migration(GO:0010764)
0.2 1.9 GO:0007379 segment specification(GO:0007379)
0.6 1.8 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.1 1.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.6 1.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.4 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.3 1.1 GO:0044307 dendritic branch(GO:0044307)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.3 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.2 0.7 GO:0043512 inhibin A complex(GO:0043512)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 194 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 2.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 2.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 1.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.7 GO:0015485 cholesterol binding(GO:0015485)
0.2 1.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.5 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.3 GO:0003823 antigen binding(GO:0003823)
0.2 1.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 1.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)