Motif ID: Hlx

Z-value: 0.269


Transcription factors associated with Hlx:

Gene SymbolEntrez IDGene Name
Hlx ENSMUSG00000039377.6 Hlx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlxmm10_v2_chr1_-_184732616_1847326270.233.0e-01Click!


Activity profile for motif Hlx.

activity profile for motif Hlx


Sorted Z-values histogram for motif Hlx

Sorted Z-values for motif Hlx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_7555053 0.531 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr9_+_54980880 0.510 ENSMUST00000093844.3
 Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_-_45103747 0.463 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr15_-_8710734 0.454 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 0.386 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_62766153 0.313 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_50094277 0.281 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chrM_+_2743 0.152 ENSMUST00000082392.1
 mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr7_-_34313531 0.101 ENSMUST00000108074.1
 4931406P16Rik
RIKEN cDNA 4931406P16 gene
chr1_-_74600564 0.060 ENSMUST00000127938.1
ENSMUST00000154874.1
 Rnf25

ring finger protein 25

chr19_+_53944870 0.058 ENSMUST00000025932.7
 Shoc2
soc-2 (suppressor of clear) homolog (C. elegans)
chr1_+_180109192 0.046 ENSMUST00000143176.1
ENSMUST00000135056.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr3_+_32436376 0.042 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr10_+_102158858 0.023 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
 Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.1 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0043205 fibril(GO:0043205)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.5 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)