Motif ID: Mbd2

Z-value: 1.319


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_705683980.116.0e-01Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_108003414 8.527 ENSMUST00000109887.1
ENSMUST00000109891.2
 Bcl11b

B cell leukemia/lymphoma 11B

chr5_+_30588078 3.955 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr5_-_115194283 3.838 ENSMUST00000112113.1
 Cabp1
calcium binding protein 1
chr11_-_75796048 3.384 ENSMUST00000021209.7
 Doc2b
double C2, beta
chr12_-_108003594 3.187 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr7_-_126082406 2.865 ENSMUST00000073935.5
 Gsg1l
GSG1-like
chr14_-_39472825 2.564 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr1_+_75375271 2.446 ENSMUST00000087122.5
 Speg
SPEG complex locus
chr6_-_126740151 2.296 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr16_-_22163299 2.276 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chrX_+_152144240 2.137 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
 Iqsec2


IQ motif and Sec7 domain 2


chr19_+_56722372 2.017 ENSMUST00000038949.4
 Adrb1
adrenergic receptor, beta 1
chr7_-_74554474 2.012 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
 Slco3a1


solute carrier organic anion transporter family, member 3a1


chr5_+_37028329 1.966 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr4_-_120747248 1.944 ENSMUST00000030376.7
 Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr6_-_72789240 1.888 ENSMUST00000069536.5
 Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr17_-_47924460 1.875 ENSMUST00000113262.1
 Foxp4
forkhead box P4
chr11_+_57645417 1.865 ENSMUST00000066987.7
ENSMUST00000108846.1
 Galnt10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10

chr2_-_166155272 1.830 ENSMUST00000088086.3
 Sulf2
sulfatase 2
chr2_-_166155624 1.814 ENSMUST00000109249.2
 Sulf2
sulfatase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 11.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 4.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.4 4.3 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.4 4.0 GO:0030322 stabilization of membrane potential(GO:0030322)
1.2 3.7 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 3.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.9 3.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 3.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 3.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 2.5 GO:0055013 cardiac muscle cell development(GO:0055013)
0.3 2.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 2.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)
0.1 2.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.7 2.0 GO:1900133 renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.2 2.0 GO:0043252 prostaglandin transport(GO:0015732) sodium-independent organic anion transport(GO:0043252)
0.5 1.9 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.4 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 3.8 GO:0071565 nBAF complex(GO:0071565)
0.9 3.4 GO:1990032 parallel fiber(GO:1990032)
0.1 3.4 GO:0031201 SNARE complex(GO:0031201)
0.1 2.9 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.8 GO:0005819 spindle(GO:0005819)
0.3 2.6 GO:0045298 tubulin complex(GO:0045298)
0.1 2.6 GO:0001741 XY body(GO:0001741)
0.2 2.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.6 GO:0070382 exocytic vesicle(GO:0070382)
0.2 1.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0034399 nuclear periphery(GO:0034399)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 4.9 GO:0008013 beta-catenin binding(GO:0008013)
0.2 4.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 4.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.7 3.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 3.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 2.3 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 2.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 2.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.7 2.0 GO:0051379 epinephrine binding(GO:0051379)
0.3 2.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 2.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 1.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.7 GO:0043008 ATP-dependent protein binding(GO:0043008)