Motif ID: Evx2

Z-value: 0.360


Transcription factors associated with Evx2:

Gene SymbolEntrez IDGene Name
Evx2 ENSMUSG00000001815.9 Evx2



Activity profile for motif Evx2.

activity profile for motif Evx2


Sorted Z-values histogram for motif Evx2

Sorted Z-values for motif Evx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Evx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 1.627 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr2_-_168767136 0.947 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr17_+_17402672 0.922 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr16_-_42340595 0.659 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr7_-_143460989 0.632 ENSMUST00000167912.1
ENSMUST00000037287.6
 Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr9_+_47530173 0.618 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
 Cadm1





cell adhesion molecule 1





chr2_-_168767029 0.560 ENSMUST00000075044.3
 Sall4
sal-like 4 (Drosophila)
chr2_+_154548888 0.420 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr9_-_66514567 0.380 ENSMUST00000056890.8
 Fbxl22
F-box and leucine-rich repeat protein 22
chr13_+_51645232 0.362 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr4_+_102570065 0.280 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_132247747 0.267 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
 Tmem230


transmembrane protein 230


chr19_+_47067721 0.257 ENSMUST00000026027.5
 Taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_+_109978004 0.255 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr5_-_84417359 0.241 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr16_-_45724600 0.231 ENSMUST00000096057.4
 Tagln3
transgelin 3
chr2_-_155074447 0.226 ENSMUST00000137242.1
ENSMUST00000054607.9
 Ahcy

S-adenosylhomocysteine hydrolase

chr7_-_126800354 0.224 ENSMUST00000106348.1
 Aldoa
aldolase A, fructose-bisphosphate
chr17_+_36837123 0.198 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26





chr10_-_80701811 0.196 ENSMUST00000003438.9
 Mob3a
MOB kinase activator 3A
chr12_+_109545390 0.195 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chr3_-_130709419 0.187 ENSMUST00000043937.7
 Ostc
oligosaccharyltransferase complex subunit
chr18_-_88927447 0.186 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr2_+_69822370 0.162 ENSMUST00000053087.3
 Klhl23
kelch-like 23
chr4_-_132345715 0.162 ENSMUST00000084250.4
 Rcc1
regulator of chromosome condensation 1
chr19_+_41933464 0.159 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr14_-_59365410 0.157 ENSMUST00000161031.1
ENSMUST00000160425.1
 Phf11d

PHD finger protein 11D

chr11_+_60537978 0.155 ENSMUST00000044250.3
 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr4_-_132345686 0.153 ENSMUST00000030726.6
 Rcc1
regulator of chromosome condensation 1
chr7_+_29816061 0.144 ENSMUST00000032796.6
ENSMUST00000178162.1
 Zfp790

zinc finger protein 790

chr1_-_184999549 0.132 ENSMUST00000027929.4
 Mark1
MAP/microtubule affinity-regulating kinase 1
chr11_+_35121126 0.127 ENSMUST00000069837.3
 Slit3
slit homolog 3 (Drosophila)
chr11_-_120378692 0.115 ENSMUST00000026448.9
 2310003H01Rik
RIKEN cDNA 2310003H01 gene
chr14_+_73173825 0.114 ENSMUST00000166875.1
 Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_31168699 0.112 ENSMUST00000033983.4
 Mak16
MAK16 homolog (S. cerevisiae)
chr6_-_69284319 0.111 ENSMUST00000103349.1
 Igkv4-69
immunoglobulin kappa variable 4-69
chr4_-_132075250 0.108 ENSMUST00000105970.1
ENSMUST00000105975.1
 Epb4.1

erythrocyte protein band 4.1

chr10_-_8886033 0.098 ENSMUST00000015449.5
 Sash1
SAM and SH3 domain containing 1
chr8_+_92855319 0.097 ENSMUST00000046290.1
 Lpcat2
lysophosphatidylcholine acyltransferase 2
chr7_+_51879041 0.079 ENSMUST00000107591.2
 Gas2
growth arrest specific 2
chr4_+_140701466 0.074 ENSMUST00000038893.5
ENSMUST00000138808.1
 Rcc2

regulator of chromosome condensation 2

chr4_-_129227883 0.073 ENSMUST00000106051.1
 C77080
expressed sequence C77080
chr7_-_44257378 0.071 ENSMUST00000107945.1
ENSMUST00000118216.1
 Acpt

acid phosphatase, testicular

chr14_+_48446128 0.065 ENSMUST00000124720.1
 Tmem260
transmembrane protein 260
chr18_-_24603791 0.051 ENSMUST00000070726.3
 Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr10_+_80264942 0.039 ENSMUST00000105362.1
ENSMUST00000105361.3
 Dazap1

DAZ associated protein 1

chr18_-_24603464 0.037 ENSMUST00000154205.1
 Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr1_-_134955908 0.034 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
 Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr8_-_35495487 0.033 ENSMUST00000033927.6
 Eri1
exoribonuclease 1
chr6_-_69400097 0.032 ENSMUST00000177795.1
 Igkv4-62
immunoglobulin kappa variable 4-62
chr6_-_124779686 0.031 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
 Lrrc23



leucine rich repeat containing 23



chr7_-_140154712 0.031 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr8_+_14888022 0.028 ENSMUST00000123990.1
ENSMUST00000027554.7
 Cln8

ceroid-lipofuscinosis, neuronal 8

chr11_+_75532099 0.022 ENSMUST00000169547.2
 Slc43a2
solute carrier family 43, member 2
chr10_+_39612934 0.013 ENSMUST00000019987.6
 Traf3ip2
TRAF3 interacting protein 2
chr19_+_5088534 0.004 ENSMUST00000025811.4
 Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr2_-_150255591 0.003 ENSMUST00000063463.5
 Gm21994
predicted gene 21994
chr2_-_84715160 0.000 ENSMUST00000035840.5
 Zdhhc5
zinc finger, DHHC domain containing 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.6 GO:0007530 sex determination(GO:0007530)
0.1 1.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.7 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.6 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)