Motif ID: Tal1
Z-value: 0.912
Transcription factors associated with Tal1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Tal1 | ENSMUSG00000028717.6 | Tal1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tal1 | mm10_v2_chr4_+_115057410_115057438 | -0.16 | 4.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 21.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.5 | 1.6 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.5 | 2.1 | GO:1903802 | positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123) |
| 0.4 | 1.4 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.4 | 1.1 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) glutamate secretion, neurotransmission(GO:0061535) |
| 0.2 | 1.7 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.2 | 0.7 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.2 | 0.7 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
| 0.2 | 0.8 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.2 | 2.2 | GO:0002693 | positive regulation of cellular extravasation(GO:0002693) |
| 0.2 | 0.2 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 0.2 | 0.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.2 | 1.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.2 | 0.6 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.2 | 2.4 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.2 | 2.0 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.2 | 0.6 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
| 0.1 | 0.4 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 0.1 | 0.8 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
| 0.1 | 0.7 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 0.3 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.1 | 0.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.6 | GO:0042167 | heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.1 | 0.4 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.1 | 1.0 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.7 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.1 | 0.5 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 0.2 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 0.1 | 1.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.6 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.1 | 0.5 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 1.3 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 0.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.1 | 0.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.2 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 0.0 | 0.8 | GO:0034377 | plasma lipoprotein particle assembly(GO:0034377) |
| 0.0 | 0.3 | GO:0032782 | bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 0.1 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.0 | 0.2 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
| 0.0 | 0.7 | GO:0007202 | activation of phospholipase C activity(GO:0007202) positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.0 | 0.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 1.6 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 0.3 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.7 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 0.3 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.0 | 2.8 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.2 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.0 | 0.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.0 | 0.3 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.0 | 0.1 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.8 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.2 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.0 | 1.5 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
| 0.0 | 0.2 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.0 | 0.4 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 0.2 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 0.0 | 0.2 | GO:1903298 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 0.0 | 0.0 | GO:0050975 | sensory perception of touch(GO:0050975) |
| 0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 1.7 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
| 0.0 | 1.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.3 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 21.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.5 | 2.1 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.4 | 1.7 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.3 | 1.7 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.3 | 2.0 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
| 0.2 | 1.7 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.3 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.1 | 0.5 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.1 | 0.5 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 0.4 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 0.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.2 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.0 | 0.7 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.2 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.8 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 0.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 1.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 0.3 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 1.3 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 2.0 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.2 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 21.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.5 | 2.0 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) |
| 0.4 | 1.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.3 | 1.7 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.2 | 1.4 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.2 | 0.7 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.2 | 0.7 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.2 | 0.6 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.2 | 0.6 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.2 | 0.9 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.2 | 1.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 0.6 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.1 | 0.4 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.1 | 0.8 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 0.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 2.1 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 1.8 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.1 | 0.4 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.1 | 0.9 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 0.5 | GO:0016803 | ether hydrolase activity(GO:0016803) |
| 0.1 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 0.7 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 2.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.2 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.0 | 0.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.0 | 0.3 | GO:0045703 | pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703) |
| 0.0 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 1.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.7 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 1.6 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 1.5 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.2 | GO:0008796 | bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796) |
| 0.0 | 0.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.2 | GO:0070513 | death domain binding(GO:0070513) |
| 0.0 | 0.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.4 | GO:0030276 | clathrin binding(GO:0030276) |
