Motif ID: Thra
Z-value: 0.622
Transcription factors associated with Thra:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Thra | ENSMUSG00000058756.7 | Thra |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Thra | mm10_v2_chr11_+_98741805_98741816 | -0.16 | 4.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
0.3 | 0.9 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.3 | 0.8 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
0.2 | 1.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.2 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.2 | 0.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.1 | 0.6 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
0.1 | 0.6 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
0.1 | 0.8 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 0.5 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.1 | 1.6 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.1 | 0.7 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.1 | 0.4 | GO:0055118 | negative regulation of cardiac muscle contraction(GO:0055118) |
0.1 | 0.7 | GO:0035902 | response to immobilization stress(GO:0035902) |
0.1 | 0.4 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
0.1 | 0.7 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 0.3 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.1 | 0.3 | GO:0097402 | neuroblast migration(GO:0097402) |
0.1 | 0.7 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.5 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.1 | 1.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
0.1 | 0.3 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.1 | 0.6 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 0.4 | GO:1903753 | cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) negative regulation of p38MAPK cascade(GO:1903753) |
0.1 | 0.5 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 1.0 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.3 | GO:0071476 | cellular hypotonic response(GO:0071476) |
0.1 | 0.2 | GO:0090202 | regulation of primitive erythrocyte differentiation(GO:0010725) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
0.1 | 0.3 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.0 | 0.2 | GO:0014719 | skeletal muscle satellite cell activation(GO:0014719) |
0.0 | 0.3 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.0 | 0.2 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
0.0 | 0.2 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.0 | 0.2 | GO:0071105 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
0.0 | 0.2 | GO:0051890 | regulation of cardioblast differentiation(GO:0051890) |
0.0 | 0.1 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
0.0 | 0.5 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
0.0 | 0.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.0 | 0.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.1 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.0 | 0.3 | GO:0019240 | citrulline biosynthetic process(GO:0019240) |
0.0 | 0.5 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
0.0 | 0.1 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.0 | 0.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.1 | GO:0000087 | mitotic M phase(GO:0000087) |
0.0 | 0.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 0.1 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.0 | 0.2 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.2 | GO:0051004 | plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004) |
0.0 | 0.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.4 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.6 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.2 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.4 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.0 | 0.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
0.0 | 0.0 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 0.5 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 0.5 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.7 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.1 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.0 | 0.2 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) type I interferon biosynthetic process(GO:0045351) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718) |
0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.1 | GO:0042473 | production of siRNA involved in RNA interference(GO:0030422) outer ear morphogenesis(GO:0042473) |
0.0 | 0.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.2 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.0 | 0.1 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.0 | 0.2 | GO:0002385 | mucosal immune response(GO:0002385) |
0.0 | 0.0 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
0.0 | 0.1 | GO:0033762 | response to glucagon(GO:0033762) |
0.0 | 0.6 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
0.0 | 0.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.2 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.1 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 0.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.1 | 0.5 | GO:0042587 | glycogen granule(GO:0042587) |
0.1 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.3 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 0.2 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.0 | 0.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 1.2 | GO:0043194 | axon initial segment(GO:0043194) |
0.0 | 0.4 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 0.1 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
0.0 | 0.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.0 | 0.5 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.3 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.3 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 0.1 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 1.3 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.2 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.2 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.2 | 0.8 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 1.0 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.5 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.4 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 0.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.2 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.1 | 0.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.1 | 0.5 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 1.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.1 | 0.4 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.0 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.0 | 0.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.2 | GO:0050693 | LBD domain binding(GO:0050693) |
0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.2 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.0 | 1.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.3 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.2 | GO:0032795 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
0.0 | 0.3 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.2 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
0.0 | 0.2 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.7 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.9 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 0.3 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.0 | 0.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.0 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.1 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.0 | 0.1 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.2 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.0 | 0.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
0.0 | 0.2 | GO:0070742 | DNA binding, bending(GO:0008301) C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.1 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |