Motif ID: Thra

Z-value: 0.622


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741805_98741816-0.164.6e-01Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 1.584 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr12_+_44328882 1.226 ENSMUST00000020939.8
ENSMUST00000110748.2
 Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr7_-_141214080 1.218 ENSMUST00000026573.5
ENSMUST00000170841.1
 1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr4_-_20778527 1.152 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr17_-_66449715 1.148 ENSMUST00000086693.5
ENSMUST00000097291.3
 Soga2

SOGA family member 2

chr10_-_92162753 1.073 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr13_-_99900645 1.073 ENSMUST00000022150.6
 Cartpt
CART prepropeptide
chr10_+_93641041 0.913 ENSMUST00000020204.4
 Ntn4
netrin 4
chr7_+_35802593 0.880 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr1_+_74791516 0.869 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr1_-_84839304 0.864 ENSMUST00000027421.6
 Trip12
thyroid hormone receptor interactor 12
chr12_-_111672290 0.814 ENSMUST00000001304.7
 Ckb
creatine kinase, brain
chr7_+_27258725 0.759 ENSMUST00000079258.6
 Numbl
numb-like
chr5_-_74065736 0.745 ENSMUST00000145016.1
 Usp46
ubiquitin specific peptidase 46
chr6_+_91157373 0.728 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chrX_+_86191764 0.719 ENSMUST00000026036.4
 Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr11_+_97450136 0.695 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr10_+_80148263 0.662 ENSMUST00000099492.3
ENSMUST00000042057.5
 Midn

midnolin

chr4_+_54947976 0.610 ENSMUST00000098070.3
 Zfp462
zinc finger protein 462
chr2_-_80128834 0.598 ENSMUST00000102654.4
ENSMUST00000102655.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 1.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 1.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 1.1 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 0.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 0.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 0.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.7 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.2 0.5 GO:0006657 CDP-choline pathway(GO:0006657)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.2 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)