Motif ID: Tbp

Z-value: 2.581


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.853.8e-07Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 18.091 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 14.932 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr14_+_68083853 13.628 ENSMUST00000022639.7
 Nefl
neurofilament, light polypeptide
chr1_-_171196229 11.100 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr1_+_109993982 8.617 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr1_-_138842429 7.971 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr13_+_21717626 7.744 ENSMUST00000091754.2
 Hist1h3h
histone cluster 1, H3h
chr13_+_113035111 7.376 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
 Cdc20b




cell division cycle 20B




chr8_+_58912257 6.881 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr13_+_110395041 6.494 ENSMUST00000022212.7
 Plk2
polo-like kinase 2
chr7_-_142899985 6.312 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr11_-_77725281 6.173 ENSMUST00000078623.4
 Cryba1
crystallin, beta A1
chr6_+_4747306 5.871 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
 Peg10


paternally expressed 10


chr6_-_136875794 5.824 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr7_-_137314394 5.682 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr7_-_103843154 5.235 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr13_+_23684192 5.199 ENSMUST00000018246.4
 Hist1h2bc
histone cluster 1, H2bc
chr2_-_164857542 5.196 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr13_+_51846673 5.131 ENSMUST00000021903.2
 Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_24251382 5.118 ENSMUST00000115390.3
 Ccnf
cyclin F

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 124 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 33.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
4.0 20.2 GO:0015671 oxygen transport(GO:0015671)
1.4 18.1 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.2 14.9 GO:0006334 nucleosome assembly(GO:0006334)
4.5 13.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.9 11.1 GO:0002227 innate immune response in mucosa(GO:0002227)
1.6 8.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 7.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 7.2 GO:0006342 chromatin silencing(GO:0006342)
0.5 6.5 GO:0032486 Rap protein signal transduction(GO:0032486)
1.6 6.3 GO:0042414 epinephrine metabolic process(GO:0042414)
0.1 5.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.9 5.3 GO:2000210 positive regulation of anoikis(GO:2000210)
1.3 5.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.3 5.2 GO:0019430 removal of superoxide radicals(GO:0019430)
0.7 5.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.5 5.1 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.8 5.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.8 4.9 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.6 4.8 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 38.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 29.2 GO:0000786 nucleosome(GO:0000786)
0.1 14.8 GO:0005814 centriole(GO:0005814)
4.5 13.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.6 12.7 GO:0005833 hemoglobin complex(GO:0005833)
0.3 8.7 GO:0005921 gap junction(GO:0005921)
0.2 7.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 7.7 GO:0005871 kinesin complex(GO:0005871)
0.3 7.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 7.1 GO:0043209 myelin sheath(GO:0043209)
0.3 6.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 5.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.6 GO:0031965 nuclear membrane(GO:0031965)
1.6 4.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 4.4 GO:0005882 intermediate filament(GO:0005882)
1.1 4.3 GO:0045098 type III intermediate filament(GO:0045098)
0.1 4.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.9 3.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 3.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.8 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 46.4 GO:0003677 DNA binding(GO:0003677)
0.2 43.6 GO:0042393 histone binding(GO:0042393)
4.0 20.2 GO:0005344 oxygen transporter activity(GO:0005344)
3.0 18.1 GO:0019841 retinol binding(GO:0019841)
0.7 15.9 GO:0043274 phospholipase binding(GO:0043274)
1.3 11.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 9.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 8.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 7.7 GO:0003777 microtubule motor activity(GO:0003777)
0.3 7.3 GO:0003785 actin monomer binding(GO:0003785)
0.2 7.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 6.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.1 6.3 GO:0035240 dopamine binding(GO:0035240)
1.3 5.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 4.9 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 4.8 GO:0005506 iron ion binding(GO:0005506)
0.2 4.3 GO:0097602 cullin family protein binding(GO:0097602)
1.4 4.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 4.0 GO:0005112 Notch binding(GO:0005112)
0.7 3.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)