Motif ID: Zbtb6

Z-value: 1.015


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37430835_374309190.262.4e-01Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102897123 6.034 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr15_+_103503261 4.960 ENSMUST00000023132.3
 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr11_-_102897146 3.766 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr9_+_23223076 3.302 ENSMUST00000071982.5
 Bmper
BMP-binding endothelial regulator
chr3_+_54156039 2.865 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr6_+_114131229 2.774 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr8_+_25518783 2.505 ENSMUST00000084027.5
ENSMUST00000117179.2
 Fgfr1

fibroblast growth factor receptor 1

chr8_+_25518757 2.443 ENSMUST00000178276.1
ENSMUST00000179592.1
 Fgfr1

fibroblast growth factor receptor 1

chr10_-_80261004 2.404 ENSMUST00000105363.1
 Gamt
guanidinoacetate methyltransferase
chr11_+_101246960 2.351 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_-_80260959 2.314 ENSMUST00000020359.6
 Gamt
guanidinoacetate methyltransferase
chr4_+_107802277 2.072 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
 Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr7_-_4789541 2.015 ENSMUST00000168578.1
 Tmem238
transmembrane protein 238
chr11_+_101246405 1.870 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2

chr7_-_105787544 1.816 ENSMUST00000078482.5
ENSMUST00000154659.1
 Dchs1

dachsous 1 (Drosophila)

chr11_-_102946688 1.768 ENSMUST00000057849.5
 C1ql1
complement component 1, q subcomponent-like 1
chr4_-_87806276 1.722 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_75549581 1.721 ENSMUST00000154101.1
 Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr11_-_94474088 1.686 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
 Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr6_+_124997062 1.642 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 9.8 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.3 6.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.7 5.0 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
1.6 4.9 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
1.6 4.7 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 4.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 4.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 3.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 3.4 GO:0007379 segment specification(GO:0007379)
0.3 3.3 GO:0042118 endothelial cell activation(GO:0042118)
0.8 3.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 2.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 1.8 GO:0061743 motor learning(GO:0061743)
0.6 1.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 1.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.5 GO:0030318 melanocyte differentiation(GO:0030318)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.2 GO:0043235 receptor complex(GO:0043235)
2.5 9.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 3.6 GO:0045177 apical part of cell(GO:0045177)
0.3 3.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.1 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.4 1.8 GO:0044301 climbing fiber(GO:0044301)
0.4 1.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.7 5.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 4.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 4.2 GO:0015026 coreceptor activity(GO:0015026)
0.2 4.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 3.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 3.0 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.2 2.9 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.9 2.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5 2.1 GO:0038025 reelin receptor activity(GO:0038025)
0.5 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 1.4 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)