Motif ID: Mtf1

Z-value: 1.066


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.048.5e-01Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 84 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94172618 16.273 ENSMUST00000034214.6
 Mt2
metallothionein 2
chr8_+_94179089 10.173 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr11_-_32222233 7.095 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr6_-_39118211 2.627 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr9_-_56635624 2.253 ENSMUST00000114256.1
 Lingo1
leucine rich repeat and Ig domain containing 1
chr9_-_112187898 1.766 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr12_-_4592927 1.737 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr4_+_129985098 1.635 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr1_+_135729147 1.593 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr4_+_129984833 1.575 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2
chr14_-_26170283 1.399 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr9_-_14381242 1.378 ENSMUST00000167549.1
 Endod1
endonuclease domain containing 1
chr3_-_94412883 1.364 ENSMUST00000181305.1
 1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr1_+_167618246 1.345 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma
chr9_+_78175898 1.320 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr7_+_5056856 1.223 ENSMUST00000131368.1
ENSMUST00000123956.1
 Ccdc106

coiled-coil domain containing 106

chr17_+_47688992 1.191 ENSMUST00000156118.1
 Frs3
fibroblast growth factor receptor substrate 3
chr10_+_70245083 1.148 ENSMUST00000046807.6
 Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr2_-_91236967 1.110 ENSMUST00000028696.4
 Ddb2
damage specific DNA binding protein 2
chr2_-_91236877 1.025 ENSMUST00000111352.1
 Ddb2
damage specific DNA binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.8 26.4 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 7.1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 2.3 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.3 2.2 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.3 2.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 1.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.6 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.5 GO:0032060 bleb assembly(GO:0032060)
0.0 1.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2 1.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.1 GO:0046415 urate metabolic process(GO:0046415)
0.3 0.9 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 0.8 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.6 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.5 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 7.0 GO:0000139 Golgi membrane(GO:0000139)
0.2 2.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.5 GO:0043218 compact myelin(GO:0043218)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 0.7 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.8 GO:0008270 zinc ion binding(GO:0008270)
0.2 10.5 GO:0005507 copper ion binding(GO:0005507)
0.1 7.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.1 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.9 GO:0031386 protein tag(GO:0031386)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.4 GO:0004519 endonuclease activity(GO:0004519)
0.1 1.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.2 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.5 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) NADPH:sulfur oxidoreductase activity(GO:0043914) epoxyqueuosine reductase activity(GO:0052693)