Motif ID: Nanog

Z-value: 0.559


Transcription factors associated with Nanog:

Gene SymbolEntrez IDGene Name
Nanog ENSMUSG00000012396.6 Nanog

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_1227076080.213.5e-01Click!


Activity profile for motif Nanog.

activity profile for motif Nanog


Sorted Z-values histogram for motif Nanog

Sorted Z-values for motif Nanog



Network of associatons between targets according to the STRING database.



First level regulatory network of Nanog

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 0.729 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr13_-_41273977 0.662 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr17_+_21691860 0.632 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr12_+_72441933 0.603 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9
chr1_-_158814469 0.553 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr12_+_72441852 0.544 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr1_-_52490736 0.512 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr10_+_58394361 0.507 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_58394381 0.505 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr2_+_134786154 0.431 ENSMUST00000110116.1
 Plcb1
phospholipase C, beta 1
chr13_-_89742244 0.395 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
 Vcan



versican



chr9_-_15357692 0.388 ENSMUST00000098979.3
ENSMUST00000161132.1
 5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr9_-_52168111 0.376 ENSMUST00000165519.1
 Zc3h12c
zinc finger CCCH type containing 12C
chr13_-_89742490 0.353 ENSMUST00000109546.2
 Vcan
versican
chr7_+_112742025 0.344 ENSMUST00000164363.1
 Tead1
TEA domain family member 1
chr9_+_92309362 0.335 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr7_+_113514085 0.311 ENSMUST00000122890.1
 Far1
fatty acyl CoA reductase 1
chr7_+_59228743 0.305 ENSMUST00000107537.1
 Ube3a
ubiquitin protein ligase E3A
chr2_+_29060239 0.292 ENSMUST00000100237.3
 Ttf1
transcription termination factor, RNA polymerase I
chr7_-_115846080 0.291 ENSMUST00000166207.1
 Sox6
SRY-box containing gene 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0070671 monocyte extravasation(GO:0035696) activation of meiosis involved in egg activation(GO:0060466) response to interleukin-12(GO:0070671) positive regulation of acrosome reaction(GO:2000344) regulation of monocyte extravasation(GO:2000437)
0.0 0.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.3 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0000801 central element(GO:0000801)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)