Motif ID: Nr1i2

Z-value: 0.864


Transcription factors associated with Nr1i2:

Gene SymbolEntrez IDGene Name
Nr1i2 ENSMUSG00000022809.4 Nr1i2



Activity profile for motif Nr1i2.

activity profile for motif Nr1i2


Sorted Z-values histogram for motif Nr1i2

Sorted Z-values for motif Nr1i2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_26210553 2.697 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr16_+_43363855 2.092 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_-_8518801 2.030 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr4_+_54945038 1.991 ENSMUST00000133895.1
 Zfp462
zinc finger protein 462
chr18_+_69346143 1.829 ENSMUST00000114980.1
 Tcf4
transcription factor 4
chr7_+_112679327 1.825 ENSMUST00000106638.2
 Tead1
TEA domain family member 1
chr5_+_13398688 1.805 ENSMUST00000125629.1
 Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_84723003 1.766 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr4_-_82705735 1.713 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr16_+_41532999 1.585 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr17_-_78985428 1.568 ENSMUST00000118991.1
 Prkd3
protein kinase D3
chr8_-_99416397 1.563 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
 Cdh8




cadherin 8




chr18_+_69345721 1.510 ENSMUST00000078486.6
ENSMUST00000114982.1
 Tcf4

transcription factor 4

chr4_-_87806296 1.500 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr16_+_23290464 1.488 ENSMUST00000115335.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr3_-_80802789 1.441 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chrX_+_86191764 1.362 ENSMUST00000026036.4
 Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr4_-_88438900 1.289 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr3_+_98013503 1.273 ENSMUST00000079812.6
 Notch2
notch 2
chr5_-_136565432 1.269 ENSMUST00000176172.1
 Cux1
cut-like homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 168 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.3 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.1 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.1 3.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 3.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 2.7 GO:0007379 segment specification(GO:0007379)
0.7 2.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 2.6 GO:0042384 cilium assembly(GO:0042384)
0.4 1.8 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.5 GO:1990743 protein sialylation(GO:1990743)
0.2 1.5 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 1.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 1.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 1.4 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.4 GO:0009409 response to cold(GO:0009409)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 1.3 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.3 1.3 GO:0060032 notochord regression(GO:0060032)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.0 GO:0031430 M band(GO:0031430)
0.1 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.5 GO:0097433 dense body(GO:0097433)
0.1 1.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.3 GO:0097542 ciliary tip(GO:0097542)
0.1 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.0 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.8 3.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 2.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.1 GO:0032452 histone demethylase activity(GO:0032452)
0.2 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 1.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 1.5 GO:0051015 actin filament binding(GO:0051015)
0.2 1.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.3 1.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.1 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)