Motif ID: Nr1i2
Z-value: 0.864
Transcription factors associated with Nr1i2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr1i2 | ENSMUSG00000022809.4 | Nr1i2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.6 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.4 | 1.3 | GO:0035622 | intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705) |
| 0.4 | 1.5 | GO:1990743 | protein sialylation(GO:1990743) |
| 0.4 | 1.8 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
| 0.3 | 3.3 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.3 | 3.0 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.3 | 1.3 | GO:0060032 | notochord regression(GO:0060032) |
| 0.3 | 3.1 | GO:0014883 | transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459) |
| 0.3 | 2.7 | GO:0007379 | segment specification(GO:0007379) |
| 0.3 | 1.0 | GO:1900157 | regulation of bone mineralization involved in bone maturation(GO:1900157) |
| 0.2 | 0.7 | GO:1900020 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.2 | 0.7 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.2 | 0.7 | GO:0060023 | soft palate development(GO:0060023) |
| 0.2 | 0.7 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 0.2 | 1.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.2 | 1.1 | GO:0071476 | cellular hypotonic response(GO:0071476) |
| 0.2 | 1.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.2 | 1.5 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
| 0.2 | 0.6 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.2 | 1.0 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.2 | 1.0 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 0.2 | 1.4 | GO:0035902 | response to immobilization stress(GO:0035902) |
| 0.2 | 1.1 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.2 | 1.8 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.2 | 0.9 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 0.3 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.2 | 0.3 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
| 0.2 | 0.5 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
| 0.2 | 0.5 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.2 | 0.6 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.1 | 0.8 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 1.1 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.1 | 0.5 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.1 | 0.7 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 0.8 | GO:1901524 | regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
| 0.1 | 0.9 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.1 | 0.6 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.1 | 0.3 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.1 | 0.3 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.1 | 1.3 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 0.4 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.1 | 0.4 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 0.3 | GO:0051695 | actin filament uncapping(GO:0051695) |
| 0.1 | 0.3 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.1 | 0.7 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 0.7 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 1.0 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 0.5 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.1 | 0.3 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 0.1 | 0.4 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 0.1 | 3.1 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 0.4 | GO:0051890 | regulation of cardioblast differentiation(GO:0051890) |
| 0.1 | 0.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 0.5 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.1 | 0.3 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.1 | 0.6 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 1.1 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 1.4 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 0.1 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.1 | 0.8 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 0.2 | GO:0090298 | negative regulation of mitochondrial DNA replication(GO:0090298) |
| 0.1 | 0.4 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
| 0.1 | 0.2 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.1 | 0.1 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.1 | 1.4 | GO:0009409 | response to cold(GO:0009409) |
| 0.1 | 0.2 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 0.1 | 0.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477) |
| 0.1 | 1.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.1 | 0.6 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.1 | 0.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 0.2 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.1 | 0.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.1 | 1.2 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.1 | 1.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.2 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.0 | 0.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.0 | 0.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.2 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.0 | 0.1 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 1.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.3 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
| 0.0 | 0.3 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.0 | 0.3 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
| 0.0 | 0.4 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.0 | 0.4 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.0 | 0.3 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.0 | 0.1 | GO:1903147 | negative regulation of mitophagy(GO:1903147) |
| 0.0 | 0.3 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.0 | 0.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.7 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.4 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.2 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
| 0.0 | 0.3 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.0 | 0.6 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.0 | 0.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.0 | 0.5 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273) |
| 0.0 | 0.2 | GO:0009992 | cellular water homeostasis(GO:0009992) |
| 0.0 | 0.3 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.0 | 0.4 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 1.2 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 0.3 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.0 | 0.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.0 | 0.5 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.0 | 0.4 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 0.2 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.0 | 0.1 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.0 | 0.5 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.0 | 0.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.0 | 0.3 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
| 0.0 | 0.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.0 | 0.2 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.3 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.0 | 0.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) asymmetric neuroblast division(GO:0055059) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.5 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.4 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.0 | 1.4 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.2 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.5 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.1 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 1.5 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 1.2 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.2 | GO:0060632 | regulation of microtubule-based movement(GO:0060632) |
| 0.0 | 0.4 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.0 | 0.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.3 | GO:0010640 | regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) |
| 0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.0 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.0 | 0.3 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 0.4 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 0.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.1 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
| 0.0 | 0.1 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.0 | 0.7 | GO:0019319 | hexose biosynthetic process(GO:0019319) |
| 0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.5 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 0.1 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.0 | 0.2 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.0 | 0.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 0.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.1 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.7 | GO:0046888 | negative regulation of hormone secretion(GO:0046888) |
| 0.0 | 0.4 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 0.2 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.1 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.3 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 2.6 | GO:0042384 | cilium assembly(GO:0042384) |
| 0.0 | 0.1 | GO:0001780 | neutrophil homeostasis(GO:0001780) negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.0 | 0.8 | GO:0006073 | glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042) |
| 0.0 | 0.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.0 | 0.0 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 0.1 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.1 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.0 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.2 | 1.5 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 0.8 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 1.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.6 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 1.0 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.1 | 1.4 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 2.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 3.0 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 0.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 1.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 1.3 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.6 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.3 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 1.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 1.9 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 0.5 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 2.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.1 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 2.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 2.0 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.2 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.2 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.0 | 0.3 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 0.4 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.9 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 0.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.9 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 0.1 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.0 | 6.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.3 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.6 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.0 | 0.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 0.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.5 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.4 | 2.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.3 | 0.9 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.3 | 1.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.3 | 1.0 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 0.7 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 0.2 | 1.4 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.2 | 0.7 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
| 0.2 | 1.5 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.2 | 0.5 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.2 | 1.9 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.2 | 0.5 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 0.4 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 1.0 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.1 | 0.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.1 | 0.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.7 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.1 | 0.3 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.1 | 0.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.3 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.1 | 2.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.5 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.1 | 0.7 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.4 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.1 | 0.4 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.1 | 0.5 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.3 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.1 | 0.3 | GO:0008488 | gamma-glutamyl carboxylase activity(GO:0008488) |
| 0.1 | 2.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.4 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.1 | 0.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.1 | 0.2 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 1.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.1 | 0.8 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 1.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 0.3 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.1 | 0.2 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 0.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 2.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 0.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.3 | GO:0034916 | 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760) |
| 0.1 | 0.3 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.6 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.0 | 0.4 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.0 | 0.5 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.5 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 1.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.5 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 0.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.0 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 0.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.0 | 0.6 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 1.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.2 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 0.2 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 1.1 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.0 | 0.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 1.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 1.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.3 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.0 | 0.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.1 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.7 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.0 | 0.8 | GO:0030546 | receptor activator activity(GO:0030546) |
| 0.0 | 0.1 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.0 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.2 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254) |
| 0.0 | 0.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.2 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.0 | 0.6 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.1 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 1.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 3.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.8 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.0 | 0.2 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.1 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.4 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.5 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.0 | 0.1 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.6 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.0 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.0 | 0.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.1 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.0 | 0.1 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.0 | 0.2 | GO:0042165 | neurotransmitter binding(GO:0042165) |
| 0.0 | 0.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 3.4 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.0 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.0 | 0.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.2 | GO:0017166 | vinculin binding(GO:0017166) receptor signaling complex scaffold activity(GO:0030159) BH domain binding(GO:0051400) |
| 0.0 | 0.1 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 0.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.0 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.0 | 0.3 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.2 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 0.5 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 1.1 | GO:0019210 | protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210) |
| 0.0 | 0.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.2 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.5 | GO:0051015 | actin filament binding(GO:0051015) |
