Motif ID: Gmeb1

Z-value: 0.366


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261596_1322616220.443.5e-02Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_40800054 0.551 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr6_+_113531675 0.540 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr3_+_40800013 0.533 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4

chr11_-_40733373 0.526 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr15_+_99074968 0.474 ENSMUST00000039665.6
 Troap
trophinin associated protein
chr1_+_175880775 0.473 ENSMUST00000039725.6
 Exo1
exonuclease 1
chr2_-_157007015 0.433 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr3_-_138143352 0.420 ENSMUST00000098580.2
 Mttp
microsomal triglyceride transfer protein
chr4_-_72200833 0.408 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
 Tle1



transducin-like enhancer of split 1, homolog of Drosophila E(spl)



chrX_+_150588223 0.318 ENSMUST00000153221.1
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_83884289 0.311 ENSMUST00000094216.3
 Mesdc1
mesoderm development candidate 1
chr2_-_157007039 0.307 ENSMUST00000103129.2
ENSMUST00000103130.1
 Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr18_+_36559972 0.292 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr15_-_83724979 0.284 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
 Scube1



signal peptide, CUB domain, EGF-like 1



chr3_+_138143483 0.276 ENSMUST00000162864.1
 Trmt10a
tRNA methyltransferase 10A
chr12_+_4917376 0.265 ENSMUST00000045664.5
 Atad2b
ATPase family, AAA domain containing 2B
chr3_+_138143429 0.253 ENSMUST00000040321.6
 Trmt10a
tRNA methyltransferase 10A
chr11_-_100822525 0.252 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr11_+_69095217 0.242 ENSMUST00000101004.2
 Per1
period circadian clock 1
chr5_-_122779278 0.228 ENSMUST00000111668.3
 Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_+_84511832 0.213 ENSMUST00000047206.5
 Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr14_+_32085804 0.211 ENSMUST00000170600.1
ENSMUST00000168986.1
ENSMUST00000169649.1
 Oxnad1


oxidoreductase NAD-binding domain containing 1


chr2_+_75659253 0.205 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
 Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr11_-_113751309 0.202 ENSMUST00000106616.1
 Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr7_+_35397046 0.199 ENSMUST00000079414.5
 Cep89
centrosomal protein 89
chr15_-_81399594 0.154 ENSMUST00000023039.8
 St13
suppression of tumorigenicity 13
chr4_+_55350043 0.151 ENSMUST00000030134.8
 Rad23b
RAD23b homolog (S. cerevisiae)
chr9_-_45906837 0.150 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
 Rnf214


ring finger protein 214


chr11_+_40733639 0.140 ENSMUST00000020578.4
 Nudcd2
NudC domain containing 2
chr11_+_86544982 0.132 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
 Tubd1



tubulin, delta 1



chr11_+_101009452 0.124 ENSMUST00000044721.6
ENSMUST00000103110.3
ENSMUST00000168757.2
 Atp6v0a1


ATPase, H+ transporting, lysosomal V0 subunit A1


chr15_-_58135047 0.122 ENSMUST00000038194.3
 Atad2
ATPase family, AAA domain containing 2
chr15_+_81400132 0.118 ENSMUST00000163754.1
ENSMUST00000041609.4
 Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr4_-_40269778 0.118 ENSMUST00000042575.6
 Topors
topoisomerase I binding, arginine/serine-rich
chr11_-_74724670 0.114 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr18_-_53744509 0.112 ENSMUST00000049811.6
 Cep120
centrosomal protein 120
chr7_+_100607410 0.112 ENSMUST00000107048.1
ENSMUST00000032946.3
 Rab6a

RAB6A, member RAS oncogene family

chr15_-_99087817 0.109 ENSMUST00000064462.3
 C1ql4
complement component 1, q subcomponent-like 4
chr15_-_81400043 0.105 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
 St13


suppression of tumorigenicity 13


chr8_-_25016901 0.103 ENSMUST00000084035.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr7_+_100607660 0.100 ENSMUST00000098252.4
 Rab6a
RAB6A, member RAS oncogene family
chr8_-_25016743 0.100 ENSMUST00000084032.5
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr4_-_126202583 0.093 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
 Thrap3


thyroid hormone receptor associated protein 3


chr4_+_128727585 0.092 ENSMUST00000106079.3
ENSMUST00000133439.1
 Phc2

polyhomeotic-like 2 (Drosophila)

chr4_-_135353126 0.090 ENSMUST00000030613.4
ENSMUST00000131373.1
 Srrm1

serine/arginine repetitive matrix 1

chr19_-_44135816 0.081 ENSMUST00000026218.5
 Cwf19l1
CWF19-like 1, cell cycle control (S. pombe)
chr13_-_53473074 0.078 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr8_-_45333189 0.074 ENSMUST00000095328.4
 Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr10_-_81378459 0.073 ENSMUST00000140901.1
 Fzr1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr16_-_87432597 0.069 ENSMUST00000039449.7
 Ltn1
listerin E3 ubiquitin protein ligase 1
chr8_+_26119611 0.068 ENSMUST00000140819.1
 Rnf170
ring finger protein 170
chr8_+_26119361 0.068 ENSMUST00000014022.8
ENSMUST00000153528.1
ENSMUST00000131138.1
ENSMUST00000110575.1
 Rnf170



ring finger protein 170



chr18_+_23954668 0.065 ENSMUST00000060762.4
 Zfp397
zinc finger protein 397
chr4_-_135353164 0.065 ENSMUST00000084846.5
ENSMUST00000136342.2
ENSMUST00000105861.1
 Srrm1


serine/arginine repetitive matrix 1


chr3_-_108086590 0.061 ENSMUST00000102638.1
ENSMUST00000102637.1
 Ampd2

adenosine monophosphate deaminase 2

chr7_+_5020376 0.056 ENSMUST00000076251.4
 Zfp865
zinc finger protein 865
chr2_+_69723071 0.053 ENSMUST00000040915.8
 Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr17_+_29549783 0.052 ENSMUST00000048677.7
 Tbc1d22b
TBC1 domain family, member 22B
chr8_+_23139030 0.052 ENSMUST00000121075.1
 Ank1
ankyrin 1, erythroid
chr3_+_127553462 0.052 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr2_+_69722797 0.051 ENSMUST00000090858.3
 Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr14_+_20694956 0.049 ENSMUST00000048016.1
 Fut11
fucosyltransferase 11
chr7_-_111082997 0.047 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
 Eif4g2



eukaryotic translation initiation factor 4, gamma 2



chr11_-_6626030 0.047 ENSMUST00000000394.7
ENSMUST00000136682.1
 Tbrg4

transforming growth factor beta regulated gene 4

chr15_-_79546741 0.043 ENSMUST00000054014.7
 Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr5_-_31291026 0.043 ENSMUST00000041565.7
 Ift172
intraflagellar transport 172
chr17_-_85090204 0.039 ENSMUST00000072406.3
ENSMUST00000171795.1
 Prepl

prolyl endopeptidase-like

chr10_-_80798476 0.038 ENSMUST00000036805.5
 Plekhj1
pleckstrin homology domain containing, family J member 1
chr4_-_126202757 0.037 ENSMUST00000080919.5
 Thrap3
thyroid hormone receptor associated protein 3
chr13_+_49653297 0.033 ENSMUST00000021824.7
 Nol8
nucleolar protein 8
chr9_+_48495345 0.030 ENSMUST00000048824.7
 Gm5617
predicted gene 5617
chr8_+_23139064 0.028 ENSMUST00000033947.8
 Ank1
ankyrin 1, erythroid
chr1_-_160212864 0.027 ENSMUST00000014370.5
 Cacybp
calcyclin binding protein
chr1_+_95313607 0.024 ENSMUST00000059975.6
 Fam174a
family with sequence similarity 174, member A
chr11_+_83302641 0.021 ENSMUST00000176430.1
ENSMUST00000065692.7
 Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr11_-_86544754 0.014 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
 Rps6kb1


ribosomal protein S6 kinase, polypeptide 1


chr11_+_97315716 0.014 ENSMUST00000019026.3
ENSMUST00000132168.1
 Mrpl45

mitochondrial ribosomal protein L45

chr7_+_5020561 0.012 ENSMUST00000085427.3
 Zfp865
zinc finger protein 865
chr8_-_123949201 0.011 ENSMUST00000044795.7
 Nup133
nucleoporin 133
chr10_+_80798652 0.010 ENSMUST00000151928.1
 Sf3a2
splicing factor 3a, subunit 2
chr19_+_43612299 0.006 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr17_-_46327949 0.003 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr6_+_90619241 0.003 ENSMUST00000032177.8
 Slc41a3
solute carrier family 41, member 3
chr19_-_41981119 0.003 ENSMUST00000026168.2
ENSMUST00000171561.1
 Mms19

MMS19 (MET18 S. cerevisiae)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.3 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.2 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0098536 deuterosome(GO:0098536)
0.1 0.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)