Motif ID: Smad4

Z-value: 0.545


Transcription factors associated with Smad4:

Gene SymbolEntrez IDGene Name
Smad4 ENSMUSG00000024515.7 Smad4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smad4mm10_v2_chr18_-_73703739_73703806-0.029.3e-01Click!


Activity profile for motif Smad4.

activity profile for motif Smad4


Sorted Z-values histogram for motif Smad4

Sorted Z-values for motif Smad4



Network of associatons between targets according to the STRING database.



First level regulatory network of Smad4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_33147400 1.775 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr1_+_153652943 1.116 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr10_+_75589363 0.999 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr7_+_101421691 0.942 ENSMUST00000163751.2
ENSMUST00000084894.7
ENSMUST00000166652.1
Pde2a


phosphodiesterase 2A, cGMP-stimulated


chr10_-_127534540 0.920 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr5_+_120431770 0.855 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr13_-_102958084 0.831 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr14_-_104467984 0.805 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr7_-_70360593 0.745 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_54039935 0.726 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr6_+_54040078 0.720 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr15_+_89532816 0.631 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr9_+_53771499 0.599 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr13_+_21735055 0.548 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr4_-_134254076 0.533 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr6_+_147032528 0.532 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr10_+_80150448 0.526 ENSMUST00000153477.1
Midn
midnolin
chr7_+_24862193 0.524 ENSMUST00000052897.4
ENSMUST00000170837.2
Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr3_-_33143227 0.502 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr11_-_89302545 0.499 ENSMUST00000061728.3
Nog
noggin
chr10_-_92164666 0.491 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr14_+_12189943 0.487 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr6_+_54039558 0.471 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chrX_+_151803642 0.465 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr17_+_72918298 0.444 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr13_-_22042949 0.437 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr17_-_28486082 0.430 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr5_+_75574916 0.416 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr5_+_92683625 0.411 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr7_+_117380937 0.408 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr2_+_27676440 0.397 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr11_-_95514570 0.394 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr13_-_98890974 0.393 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr6_-_138422898 0.382 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr5_-_137741102 0.370 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chrX_+_136270253 0.370 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr4_-_117178726 0.370 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr9_-_45936049 0.367 ENSMUST00000034590.2
Tagln
transgelin
chr9_-_14381242 0.366 ENSMUST00000167549.1
Endod1
endonuclease domain containing 1
chr7_-_45052865 0.352 ENSMUST00000057293.6
Prr12
proline rich 12
chr3_-_96220880 0.342 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chrX_+_136270302 0.336 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr15_+_39076885 0.336 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr6_-_72958097 0.331 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr1_+_187997821 0.326 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr2_+_120476911 0.320 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr15_-_38300693 0.316 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr17_-_70851710 0.316 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr1_+_187997835 0.315 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr2_+_3114220 0.311 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr11_+_60699718 0.306 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr14_-_54577578 0.298 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr1_-_16770138 0.293 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr8_-_34146974 0.276 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chrX_+_99136119 0.273 ENSMUST00000052839.6
Efnb1
ephrin B1
chr6_+_108660772 0.269 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr11_+_60699758 0.261 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr13_-_21832194 0.257 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr19_-_40271506 0.251 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr11_-_3504766 0.248 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr6_-_72958465 0.246 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr19_-_31664356 0.242 ENSMUST00000073581.5
Prkg1
protein kinase, cGMP-dependent, type I
chr16_-_55283237 0.240 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr12_-_109600328 0.237 ENSMUST00000149046.2
Rtl1
retrotransposon-like 1
chr4_+_128688726 0.234 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr5_+_7179299 0.231 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chrX_+_150588223 0.229 ENSMUST00000153221.1
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_141216626 0.228 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr11_-_69413675 0.228 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr8_+_45658273 0.226 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chrX_-_136741155 0.225 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr4_-_134245579 0.224 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr9_-_21852603 0.223 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr4_+_42950369 0.221 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_-_109251698 0.219 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chrX_+_151803313 0.217 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr7_+_45785331 0.214 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr1_-_64121389 0.214 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr17_+_24352037 0.213 ENSMUST00000079594.5
Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr14_+_64950037 0.210 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr13_-_115090123 0.209 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr19_+_4097392 0.202 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr9_-_49798905 0.200 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr7_-_126897424 0.197 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr10_-_91082704 0.197 ENSMUST00000162618.1
ENSMUST00000020157.6
ENSMUST00000160788.1
Apaf1


apoptotic peptidase activating factor 1


chr17_-_35162969 0.194 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr14_+_50944499 0.193 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr6_-_83775767 0.191 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr11_-_106160101 0.189 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chrX_-_150588071 0.188 ENSMUST00000140207.1
ENSMUST00000112719.1
ENSMUST00000112727.3
ENSMUST00000112721.3
ENSMUST00000026303.9
Apex2




apurinic/apyrimidinic endonuclease 2




chr10_+_80300997 0.187 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr1_-_54194048 0.180 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr8_-_41016749 0.179 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr13_+_23531044 0.178 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr13_-_23551648 0.176 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr19_-_5295397 0.175 ENSMUST00000025774.9
Sf3b2
splicing factor 3b, subunit 2
chr15_-_27681498 0.174 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr7_-_30362772 0.174 ENSMUST00000046351.5
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr11_-_106160708 0.168 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr7_+_83755904 0.167 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr11_-_106159902 0.165 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chr4_+_117835387 0.158 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr14_+_57826210 0.156 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chr7_+_45216671 0.155 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr9_+_96895617 0.152 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chrX_-_72274747 0.151 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr12_+_103314944 0.150 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr7_+_45215753 0.150 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr6_-_30693676 0.148 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr2_+_27079371 0.145 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr5_+_30913398 0.136 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chrX_+_56779437 0.135 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr2_+_32628390 0.126 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr7_+_141949846 0.124 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr2_-_93046053 0.122 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr19_+_46328179 0.121 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr9_+_106429537 0.120 ENSMUST00000059802.6
Rpl29
ribosomal protein L29
chr9_-_57552760 0.114 ENSMUST00000034856.8
Mpi
mannose phosphate isomerase
chr8_-_92356103 0.112 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr1_-_173367638 0.112 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr9_+_61373608 0.110 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr5_+_121795034 0.109 ENSMUST00000162327.1
Atxn2
ataxin 2
chr3_-_146839365 0.108 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr9_+_21424984 0.108 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2

dynamin 2

chr7_+_127485221 0.108 ENSMUST00000048896.6
Fbrs
fibrosin
chr3_+_68572245 0.105 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr11_+_4160348 0.104 ENSMUST00000002198.3
Sf3a1
splicing factor 3a, subunit 1
chr4_+_126677630 0.104 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr3_+_88607742 0.102 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr9_-_49798729 0.101 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr9_+_61373482 0.099 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr4_-_129742275 0.099 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr17_+_46646225 0.098 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr12_+_13269111 0.097 ENSMUST00000042953.8
Nbas
neuroblastoma amplified sequence
chr11_-_5261558 0.096 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr9_+_122888471 0.096 ENSMUST00000063980.6
Zkscan7
zinc finger with KRAB and SCAN domains 7
chr14_-_54554359 0.090 ENSMUST00000022784.8
Haus4
HAUS augmin-like complex, subunit 4
chr13_+_22043189 0.090 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr9_-_20898592 0.089 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr2_+_119547697 0.082 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr14_-_18331855 0.082 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr10_+_127739516 0.079 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chr9_+_59589288 0.077 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr4_-_95052170 0.075 ENSMUST00000058555.2
Jun
Jun oncogene
chr10_-_91082653 0.075 ENSMUST00000159110.1
Apaf1
apoptotic peptidase activating factor 1
chr3_+_127633134 0.074 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr5_-_123684289 0.072 ENSMUST00000111564.1
ENSMUST00000063905.5
Clip1

CAP-GLY domain containing linker protein 1

chrX_-_7898950 0.070 ENSMUST00000115655.1
ENSMUST00000156741.1
Pqbp1

polyglutamine binding protein 1

chr9_-_105521147 0.069 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr3_+_36552600 0.065 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr11_-_115419917 0.060 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr1_+_152399824 0.059 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr2_+_70562854 0.058 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr18_-_84086379 0.056 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr5_-_24445166 0.055 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr7_+_4690760 0.055 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr9_+_61373219 0.055 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr19_-_8818924 0.055 ENSMUST00000153281.1
Ttc9c
tetratricopeptide repeat domain 9C
chrX_-_7898864 0.053 ENSMUST00000154552.1
Pqbp1
polyglutamine binding protein 1
chr13_-_98891036 0.052 ENSMUST00000109399.2
Tnpo1
transportin 1
chr15_-_98728120 0.050 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr6_+_116650674 0.050 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr4_+_97772734 0.049 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr2_+_152226839 0.049 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1


casein kinase 2, alpha 1 polypeptide


chr12_-_36156781 0.048 ENSMUST00000020856.4
Bzw2
basic leucine zipper and W2 domains 2
chr5_-_24445254 0.048 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr4_+_116221590 0.048 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr4_+_130055010 0.046 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr14_-_64949632 0.045 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr5_+_111417263 0.044 ENSMUST00000094463.4
Mn1
meningioma 1
chr3_+_96221111 0.043 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr14_-_31168587 0.043 ENSMUST00000036618.7
Stab1
stabilin 1
chr11_+_115420059 0.042 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr7_+_141949982 0.042 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr18_+_60526194 0.041 ENSMUST00000025505.5
Dctn4
dynactin 4
chr19_-_23448322 0.041 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr4_+_127172866 0.040 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr4_+_116221689 0.037 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr10_+_33905015 0.036 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr11_+_4637734 0.031 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr2_+_127247908 0.024 ENSMUST00000035871.8
ENSMUST00000174503.1
ENSMUST00000174288.1
Tmem127


transmembrane protein 127


chr8_+_95825353 0.023 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr15_+_81936911 0.021 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr7_+_123377982 0.018 ENSMUST00000033025.5
Lcmt1
leucine carboxyl methyltransferase 1
chr12_-_12941827 0.015 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr15_-_93336800 0.014 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr1_-_74588117 0.012 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr16_+_34784917 0.011 ENSMUST00000023538.8
Mylk
myosin, light polypeptide kinase
chr10_+_91082940 0.011 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr11_-_102319093 0.011 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf


upstream binding transcription factor, RNA polymerase I


chr15_-_103366763 0.010 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr17_+_34263209 0.005 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr12_+_76404168 0.002 ENSMUST00000080449.5
Hspa2
heat shock protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.3 0.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.4 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.2 0.8 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.1 0.7 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 1.0 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.6 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.5 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.9 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.5 GO:0033572 transferrin transport(GO:0033572)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0046103 ADP biosynthetic process(GO:0006172) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657) cellular response to potassium ion starvation(GO:0051365)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 0.9 GO:0036004 GAF domain binding(GO:0036004)
0.2 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.0 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)