Motif ID: Hoxa1

Z-value: 1.240


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_96862903 10.057 ENSMUST00000121077.1
ENSMUST00000124923.1
 Acpl2

acid phosphatase-like 2

chr3_+_55782500 7.557 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr9_+_15239045 6.419 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr2_+_158375638 5.694 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr2_+_165595009 4.717 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)
chr4_-_143299498 4.671 ENSMUST00000030317.7
 Pdpn
podoplanin
chr19_-_41743665 4.665 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr7_+_73391160 4.448 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr2_-_26246707 4.273 ENSMUST00000166349.1
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr1_+_153665274 3.788 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr14_+_70077375 3.598 ENSMUST00000035908.1
 Egr3
early growth response 3
chr2_+_163225363 3.472 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr4_-_35845204 3.402 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr3_-_110143937 3.229 ENSMUST00000051253.3
 Ntng1
netrin G1
chr10_+_26078255 2.927 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr15_-_95528702 2.703 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr15_+_98167806 2.613 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr2_+_152962485 2.507 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr5_+_27261916 2.322 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr10_-_63421739 1.960 ENSMUST00000054760.4
 Gm7075
predicted gene 7075
chr4_-_143299463 1.914 ENSMUST00000119654.1
 Pdpn
podoplanin
chr4_-_106799779 1.731 ENSMUST00000145061.1
ENSMUST00000102762.3
 Acot11

acyl-CoA thioesterase 11

chr10_-_92162753 1.558 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr6_-_136875794 1.517 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr9_+_65890237 1.498 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_-_52012476 1.475 ENSMUST00000078214.5
 Skap2
src family associated phosphoprotein 2
chr7_-_30534180 1.457 ENSMUST00000044338.4
 Arhgap33
Rho GTPase activating protein 33
chr7_-_16917184 1.423 ENSMUST00000173139.1
 Calm3
calmodulin 3
chr4_+_128688726 1.398 ENSMUST00000106080.1
 Phc2
polyhomeotic-like 2 (Drosophila)
chr18_-_13972617 1.396 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr18_+_4994600 1.391 ENSMUST00000140448.1
 Svil
supervillin
chr12_+_53248677 1.319 ENSMUST00000101432.2
 Npas3
neuronal PAS domain protein 3
chr2_+_65845767 1.312 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_90885860 1.236 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr10_+_94576254 1.199 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr13_-_60177357 1.169 ENSMUST00000065086.4
 Gas1
growth arrest specific 1
chr2_+_65845833 1.145 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_+_101507855 1.030 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_-_8639363 1.020 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr4_+_101507947 1.018 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr10_+_14523062 0.922 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr3_-_89093358 0.889 ENSMUST00000090929.5
ENSMUST00000052539.6
 Rusc1

RUN and SH3 domain containing 1

chr5_+_88583527 0.710 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr1_+_10993452 0.688 ENSMUST00000027056.5
 Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr13_+_72628802 0.656 ENSMUST00000074372.4
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr3_-_58525867 0.642 ENSMUST00000029385.7
 Serp1
stress-associated endoplasmic reticulum protein 1
chr15_+_74516196 0.620 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr8_+_95825353 0.611 ENSMUST00000074053.4
 Gm10094
predicted gene 10094
chr17_-_25081138 0.562 ENSMUST00000024984.6
 Tmem204
transmembrane protein 204
chr9_+_58129476 0.549 ENSMUST00000133287.1
 Stra6
stimulated by retinoic acid gene 6
chr11_+_24080664 0.548 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr9_-_4796218 0.495 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
 Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr9_+_59589288 0.471 ENSMUST00000121266.1
ENSMUST00000118164.1
 Celf6

CUGBP, Elav-like family member 6

chr11_+_103774150 0.446 ENSMUST00000000127.5
 Wnt3
wingless-related MMTV integration site 3
chr9_-_21312255 0.446 ENSMUST00000115433.3
ENSMUST00000003397.7
 Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr16_-_18876522 0.417 ENSMUST00000119273.1
 Mrpl40
mitochondrial ribosomal protein L40
chr11_-_102296618 0.387 ENSMUST00000107132.2
ENSMUST00000073234.2
 Atxn7l3

ataxin 7-like 3

chr6_-_88446491 0.367 ENSMUST00000165242.1
 Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr14_-_69503316 0.343 ENSMUST00000179116.2
 Gm21464
predicted gene, 21464
chr1_+_89454769 0.333 ENSMUST00000027521.8
ENSMUST00000074945.5
 Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr11_-_40755201 0.319 ENSMUST00000020576.7
 Ccng1
cyclin G1
chr10_+_79988584 0.314 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr18_+_56562443 0.306 ENSMUST00000130163.1
ENSMUST00000132628.1
 Phax

phosphorylated adaptor for RNA export

chr17_-_28622479 0.301 ENSMUST00000130643.1
 Srpk1
serine/arginine-rich protein specific kinase 1
chrX_-_75578188 0.285 ENSMUST00000033545.5
 Rab39b
RAB39B, member RAS oncogene family
chr17_-_90455872 0.256 ENSMUST00000174337.1
ENSMUST00000172466.1
 Nrxn1

neurexin I

chr8_-_67515606 0.247 ENSMUST00000032981.5
 Gm9755
predicted pseudogene 9755
chr16_-_18876655 0.243 ENSMUST00000023391.8
 Mrpl40
mitochondrial ribosomal protein L40
chr7_+_144838590 0.214 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr9_+_58129321 0.205 ENSMUST00000034880.3
 Stra6
stimulated by retinoic acid gene 6
chr12_-_80260356 0.197 ENSMUST00000021554.8
 Actn1
actinin, alpha 1
chr9_+_58129062 0.196 ENSMUST00000085677.2
 Stra6
stimulated by retinoic acid gene 6
chr11_-_5898771 0.189 ENSMUST00000102921.3
 Myl7
myosin, light polypeptide 7, regulatory
chr6_+_91684061 0.188 ENSMUST00000032185.7
 Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chrX_+_38600626 0.187 ENSMUST00000000365.2
 Mcts1
malignant T cell amplified sequence 1
chr2_-_152951688 0.168 ENSMUST00000109811.3
 Dusp15
dual specificity phosphatase-like 15
chr17_+_78491549 0.165 ENSMUST00000079363.4
 Gm10093
predicted pseudogene 10093
chr5_+_137030275 0.159 ENSMUST00000041543.8
 Vgf
VGF nerve growth factor inducible
chr17_+_55445375 0.146 ENSMUST00000133899.1
ENSMUST00000086878.3
 St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr13_+_72628831 0.145 ENSMUST00000169028.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr2_+_112261926 0.133 ENSMUST00000028553.3
 Nop10
NOP10 ribonucleoprotein
chr3_-_79145875 0.131 ENSMUST00000118340.1
 Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_28622419 0.121 ENSMUST00000114767.1
 Srpk1
serine/arginine-rich protein specific kinase 1
chr7_+_3694512 0.114 ENSMUST00000108627.3
 Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chrX_-_134161928 0.106 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr7_+_119690026 0.097 ENSMUST00000047045.8
 Acsm4
acyl-CoA synthetase medium-chain family member 4
chr5_+_135369942 0.092 ENSMUST00000000940.8
 Nsun5
NOL1/NOP2/Sun domain family, member 5
chr14_+_66344369 0.060 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
 Stmn4



stathmin-like 4



chr5_+_42067960 0.036 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr10_+_75037291 0.026 ENSMUST00000139384.1
 Rab36
RAB36, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.7 4.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.7 6.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.4 4.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 2.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 3.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 3.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 2.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 0.9 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 1.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 1.3 GO:0042711 maternal behavior(GO:0042711)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.1 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 2.3 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 3.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 4.3 GO:0043010 camera-type eye development(GO:0043010)
0.0 1.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 3.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 6.3 GO:0030175 filopodium(GO:0030175)
0.0 3.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.6 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.6 4.7 GO:0048495 Roundabout binding(GO:0048495)
0.4 1.4 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 4.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 3.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.7 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.1 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 6.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 3.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)