Motif ID: Hoxa1

Z-value: 1.240


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_96862903 10.057 ENSMUST00000121077.1
ENSMUST00000124923.1
 Acpl2

acid phosphatase-like 2

chr3_+_55782500 7.557 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr9_+_15239045 6.419 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr2_+_158375638 5.694 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr2_+_165595009 4.717 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)
chr4_-_143299498 4.671 ENSMUST00000030317.7
 Pdpn
podoplanin
chr19_-_41743665 4.665 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr7_+_73391160 4.448 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr2_-_26246707 4.273 ENSMUST00000166349.1
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr1_+_153665274 3.788 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr14_+_70077375 3.598 ENSMUST00000035908.1
 Egr3
early growth response 3
chr2_+_163225363 3.472 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr4_-_35845204 3.402 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr3_-_110143937 3.229 ENSMUST00000051253.3
 Ntng1
netrin G1
chr10_+_26078255 2.927 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr15_-_95528702 2.703 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr15_+_98167806 2.613 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr2_+_152962485 2.507 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr5_+_27261916 2.322 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr10_-_63421739 1.960 ENSMUST00000054760.4
 Gm7075
predicted gene 7075

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 6.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.7 4.7 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.7 4.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 4.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 4.3 GO:0043010 camera-type eye development(GO:0043010)
0.3 3.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 3.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 3.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 2.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.3 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 2.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 1.3 GO:0042711 maternal behavior(GO:0042711)
0.1 1.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 1.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 0.9 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.3 GO:0030175 filopodium(GO:0030175)
0.1 4.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.6 6.6 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.6 4.7 GO:0048495 Roundabout binding(GO:0048495)
0.3 4.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 3.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.7 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.1 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 1.4 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)