Motif ID: Klf15

Z-value: 0.950


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90465287_904653040.744.7e-05Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56971762 5.044 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr11_-_54068932 3.945 ENSMUST00000093109.4
ENSMUST00000018755.3
 Pdlim4

PDZ and LIM domain 4

chr19_+_5740885 3.352 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr18_-_89769479 3.071 ENSMUST00000097495.3
 Dok6
docking protein 6
chr11_+_50602072 2.999 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr1_-_56972437 2.767 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr10_-_81430966 2.727 ENSMUST00000117966.1
 Nfic
nuclear factor I/C
chr15_+_57694651 2.652 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr10_-_127666598 2.588 ENSMUST00000099157.3
 Nab2
Ngfi-A binding protein 2
chr9_-_79718631 2.574 ENSMUST00000180083.1
 Col12a1
collagen, type XII, alpha 1
chr9_-_79718518 2.452 ENSMUST00000071750.6
 Col12a1
collagen, type XII, alpha 1
chr17_+_75005523 2.436 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr10_-_127666673 2.200 ENSMUST00000026469.2
 Nab2
Ngfi-A binding protein 2
chr1_+_59482133 2.060 ENSMUST00000114246.2
ENSMUST00000037105.6
 Fzd7

frizzled homolog 7 (Drosophila)

chr11_-_59964936 1.975 ENSMUST00000062405.7
 Rasd1
RAS, dexamethasone-induced 1
chr5_+_64803513 1.971 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr7_+_122289297 1.925 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr5_+_137288273 1.921 ENSMUST00000024099.4
ENSMUST00000085934.3
 Ache

acetylcholinesterase

chr11_+_69765970 1.874 ENSMUST00000108642.1
ENSMUST00000156932.1
 Zbtb4

zinc finger and BTB domain containing 4

chr1_+_42697146 1.821 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 134 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 4.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
1.1 3.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 3.0 GO:0030574 collagen catabolic process(GO:0030574)
0.1 2.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.5 2.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 2.6 GO:0006402 mRNA catabolic process(GO:0006402)
0.5 2.4 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 2.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.5 2.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 2.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.3 1.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 1.9 GO:0019695 choline metabolic process(GO:0019695)
0.6 1.8 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.4 1.8 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.3 1.7 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 1.6 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.7 GO:0000118 histone deacetylase complex(GO:0000118)
1.7 5.0 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 2.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.8 GO:0030175 filopodium(GO:0030175)
0.0 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.8 2.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.9 GO:0005605 basal lamina(GO:0005605)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.1 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)
0.4 1.4 GO:0043293 apoptosome(GO:0043293)
0.2 1.4 GO:1990246 uniplex complex(GO:1990246)
0.1 1.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 3.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 3.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.6 2.4 GO:0050436 microfibril binding(GO:0050436)
0.3 2.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.5 1.9 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 1.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 1.9 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 1.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)