Motif ID: Nr6a1

Z-value: 0.475


Transcription factors associated with Nr6a1:

Gene SymbolEntrez IDGene Name
Nr6a1 ENSMUSG00000063972.7 Nr6a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_389264540.116.2e-01Click!


Activity profile for motif Nr6a1.

activity profile for motif Nr6a1


Sorted Z-values histogram for motif Nr6a1

Sorted Z-values for motif Nr6a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr6a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_79858627 2.168 ENSMUST00000027467.4
 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr4_+_13743424 1.733 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_+_12189943 1.447 ENSMUST00000119888.1
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr14_+_58072686 1.306 ENSMUST00000022545.7
 Fgf9
fibroblast growth factor 9
chr17_+_72918298 1.302 ENSMUST00000024857.6
 Lbh
limb-bud and heart
chr19_+_46707443 1.288 ENSMUST00000003655.7
 As3mt
arsenic (+3 oxidation state) methyltransferase
chr15_-_98165613 1.082 ENSMUST00000143400.1
 Asb8
ankyrin repeat and SOCS box-containing 8
chr11_-_69822144 1.045 ENSMUST00000045771.6
 Spem1
sperm maturation 1
chr9_-_96437434 1.008 ENSMUST00000070500.2
 BC043934
cDNA sequence BC043934
chr12_+_3807017 0.972 ENSMUST00000020991.8
ENSMUST00000172509.1
 Dnmt3a

DNA methyltransferase 3A

chr2_+_172472512 0.881 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr12_+_3807076 0.844 ENSMUST00000174817.1
 Dnmt3a
DNA methyltransferase 3A
chr5_-_137610626 0.844 ENSMUST00000142675.1
 Pcolce
procollagen C-endopeptidase enhancer protein
chr13_-_24761440 0.820 ENSMUST00000176890.1
ENSMUST00000175689.1
 Gmnn

geminin

chr7_+_16944645 0.755 ENSMUST00000094807.5
 Pnmal2
PNMA-like 2
chr4_-_45530330 0.741 ENSMUST00000061986.5
 Shb
src homology 2 domain-containing transforming protein B
chr4_+_123904907 0.735 ENSMUST00000106202.3
 Mycbp
c-myc binding protein
chr10_+_128083273 0.704 ENSMUST00000026459.5
 Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr5_-_107972864 0.691 ENSMUST00000153172.1
 Fam69a
family with sequence similarity 69, member A
chr4_+_123904832 0.675 ENSMUST00000030400.7
 Mycbp
c-myc binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.2 1.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 1.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.1 1.3 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.3 GO:0060484 male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484)
0.0 1.3 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 1.0 GO:0030317 sperm motility(GO:0030317)
0.1 0.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 0.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 0.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.5 GO:0003341 cilium movement(GO:0003341)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.3 GO:0009838 abscission(GO:0009838)
0.1 0.3 GO:0046078 dUMP metabolic process(GO:0046078)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0031091 platelet alpha granule(GO:0031091) extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.8 GO:0001741 XY body(GO:0001741)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.1 0.4 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.8 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 1.8 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.2 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0015035 glutathione peroxidase activity(GO:0004602) protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)