Motif ID: Fosl2_Bach2

Z-value: 0.587

Transcription factors associated with Fosl2_Bach2:

Gene SymbolEntrez IDGene Name
Bach2 ENSMUSG00000040270.10 Bach2
Fosl2 ENSMUSG00000029135.9 Fosl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosl2mm10_v2_chr5_+_32136458_321365050.482.1e-02Click!
Bach2mm10_v2_chr4_+_32238713_32238804-0.242.8e-01Click!


Activity profile for motif Fosl2_Bach2.

activity profile for motif Fosl2_Bach2


Sorted Z-values histogram for motif Fosl2_Bach2

Sorted Z-values for motif Fosl2_Bach2



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosl2_Bach2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1286563 3.109 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr6_+_17463927 2.690 ENSMUST00000115442.1
 Met
met proto-oncogene
chr7_-_105482197 2.036 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr14_+_65968483 1.837 ENSMUST00000022616.6
 Clu
clusterin
chr14_+_101840602 1.569 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr7_-_44670820 1.552 ENSMUST00000048102.7
 Myh14
myosin, heavy polypeptide 14
chr2_+_91257323 1.377 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr10_+_128933782 1.348 ENSMUST00000099112.2
 Itga7
integrin alpha 7
chr18_+_32938955 1.327 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr14_+_101840501 1.313 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr16_-_22439719 1.303 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr6_+_17463749 1.257 ENSMUST00000115443.1
 Met
met proto-oncogene
chr2_-_45110241 1.223 ENSMUST00000177302.1
 Zeb2
zinc finger E-box binding homeobox 2
chr8_-_120228221 1.204 ENSMUST00000183235.1
 A330074K22Rik
RIKEN cDNA A330074K22 gene
chr6_+_124996681 1.138 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr3_-_88503331 1.131 ENSMUST00000029699.6
 Lmna
lamin A
chr6_-_97459279 1.113 ENSMUST00000113359.1
 Frmd4b
FERM domain containing 4B
chr2_-_166581969 1.105 ENSMUST00000109246.1
 Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr10_-_81407641 1.076 ENSMUST00000140916.1
 Nfic
nuclear factor I/C
chr4_-_140665891 1.071 ENSMUST00000069623.5
 Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.7 2.0 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.5 2.0 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 1.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.3 1.8 GO:0015862 uridine transport(GO:0015862)
0.4 1.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 1.7 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.7 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 1.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.3 1.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 1.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 1.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.1 2.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 2.0 GO:0005638 lamin filament(GO:0005638)
0.3 1.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.3 1.6 GO:0097513 myosin II filament(GO:0097513)
0.1 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.1 GO:0005901 caveola(GO:0005901)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.3 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.1 0.8 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.2 0.7 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 4.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 3.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.9 GO:0042805 actinin binding(GO:0042805)
0.0 2.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 1.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)