Motif ID: Pou2f1

Z-value: 0.674


Transcription factors associated with Pou2f1:

Gene SymbolEntrez IDGene Name
Pou2f1 ENSMUSG00000026565.12 Pou2f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou2f1mm10_v2_chr1_-_166002613_166002678-0.631.2e-03Click!


Activity profile for motif Pou2f1.

activity profile for motif Pou2f1


Sorted Z-values histogram for motif Pou2f1

Sorted Z-values for motif Pou2f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 7.918 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr4_+_13751297 2.519 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_133688978 2.433 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr5_-_5266038 1.958 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr18_+_86711520 1.900 ENSMUST00000122464.1
Cbln2
cerebellin 2 precursor protein
chr2_-_127831817 1.893 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr12_-_108003594 1.881 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr1_+_109983737 1.768 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr12_+_38783455 1.701 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr11_-_84525514 1.611 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr13_+_83573577 1.369 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr12_-_108003414 1.349 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr11_+_84525647 1.338 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr11_+_84525669 1.317 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr4_+_134510999 1.258 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chrX_+_42526585 1.213 ENSMUST00000101619.3
Gm10483
predicted gene 10483
chrX_-_10216437 1.095 ENSMUST00000115534.1
Rpgr
retinitis pigmentosa GTPase regulator
chr13_+_23684192 1.058 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr1_-_138856819 1.035 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr10_-_109009055 1.010 ENSMUST00000156979.1
Syt1
synaptotagmin I

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.5 3.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 2.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 2.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 2.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 1.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.5 1.6 GO:0060067 cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 1.5 GO:0007051 spindle organization(GO:0007051)
0.5 1.4 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 1.4 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.2 1.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 0.9 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 0.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 2.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 1.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.1 GO:0000922 spindle pole(GO:0000922)
0.2 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.2 0.9 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.2 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.1 0.5 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.5 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 1.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.7 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.2 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.6 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.2 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)