Motif ID: Zfp652

Z-value: 0.850


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95749067_95749067-0.087.0e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 6.981 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr5_-_53707532 6.100 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr1_+_153665666 3.646 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_-_138847579 3.503 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr1_+_153665274 3.410 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr10_-_92165159 3.205 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr4_-_63403330 3.139 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr10_-_6980376 3.126 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr1_+_153665587 2.885 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 2.811 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr5_-_24351604 1.992 ENSMUST00000036092.7
 Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_-_17176888 1.851 ENSMUST00000170580.1
 Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr9_-_108452377 1.727 ENSMUST00000035232.7
 Klhdc8b
kelch domain containing 8B
chr4_-_35845204 1.722 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr11_+_98960412 1.690 ENSMUST00000107473.2
 Rara
retinoic acid receptor, alpha
chr11_-_94242701 1.679 ENSMUST00000061469.3
 Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr14_-_70627008 1.664 ENSMUST00000110984.2
 Dmtn
dematin actin binding protein
chr9_+_75775355 1.659 ENSMUST00000012281.7
 Bmp5
bone morphogenetic protein 5
chr9_+_21165714 1.610 ENSMUST00000039413.8
 Pde4a
phosphodiesterase 4A, cAMP specific
chr19_-_4928241 1.518 ENSMUST00000025851.3
 Dpp3
dipeptidylpeptidase 3
chr10_+_75589363 1.490 ENSMUST00000072217.2
 Ggt5
gamma-glutamyltransferase 5
chr15_-_64382736 1.478 ENSMUST00000176384.1
ENSMUST00000175799.1
 Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr11_+_62820469 1.417 ENSMUST00000108703.1
 Trim16
tripartite motif-containing 16
chr4_-_134254076 1.358 ENSMUST00000060050.5
 Grrp1
glycine/arginine rich protein 1
chr5_+_115908644 1.338 ENSMUST00000141101.1
 Cit
citron
chr10_-_7792795 1.264 ENSMUST00000065124.1
 6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr14_+_55853997 1.209 ENSMUST00000100529.3
 Nynrin
NYN domain and retroviral integrase containing
chr15_-_64382908 1.160 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
 Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr3_+_87971071 1.071 ENSMUST00000090973.5
 Nes
nestin
chr3_+_87971129 1.051 ENSMUST00000160694.1
 Nes
nestin
chr1_+_184034381 1.034 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chr6_+_124808885 1.031 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
 Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr6_+_83137089 0.950 ENSMUST00000121093.1
ENSMUST00000087938.4
 Rtkn

rhotekin

chr2_-_84743655 0.945 ENSMUST00000181711.1
 Gm19426
predicted gene, 19426
chr2_-_84886692 0.935 ENSMUST00000054514.5
ENSMUST00000151799.1
 Rtn4rl2

reticulon 4 receptor-like 2

chr4_+_128654686 0.924 ENSMUST00000030588.6
ENSMUST00000136377.1
 Phc2

polyhomeotic-like 2 (Drosophila)

chr12_+_55598917 0.851 ENSMUST00000051857.3
 Insm2
insulinoma-associated 2
chr11_+_23666479 0.842 ENSMUST00000143117.1
 Pus10
pseudouridylate synthase 10
chr6_+_137754529 0.780 ENSMUST00000087675.6
 Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr6_-_99028251 0.758 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
 Foxp1



forkhead box P1



chr1_-_167285110 0.736 ENSMUST00000027839.8
 Uck2
uridine-cytidine kinase 2
chr1_-_118982551 0.705 ENSMUST00000159678.1
 Gli2
GLI-Kruppel family member GLI2
chr1_-_184033998 0.659 ENSMUST00000050306.5
 1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr9_+_44334685 0.651 ENSMUST00000052686.2
 H2afx
H2A histone family, member X
chr19_-_30549516 0.647 ENSMUST00000025803.8
 Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr14_+_73237891 0.630 ENSMUST00000044405.6
 Lpar6
lysophosphatidic acid receptor 6
chr9_+_108854024 0.622 ENSMUST00000098376.3
 Slc26a6
solute carrier family 26, member 6
chr17_-_32388885 0.619 ENSMUST00000087703.5
ENSMUST00000170603.1
 Wiz

widely-interspaced zinc finger motifs

chr11_+_46055973 0.583 ENSMUST00000011400.7
 Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr6_-_99028874 0.548 ENSMUST00000154163.2
 Foxp1
forkhead box P1
chr6_+_50110837 0.535 ENSMUST00000167628.1
 Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr11_+_70018728 0.520 ENSMUST00000018700.6
ENSMUST00000134376.2
 Dlg4

discs, large homolog 4 (Drosophila)

chr3_+_90072641 0.517 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
 Tpm3


tropomyosin 3, gamma


chr11_-_109472611 0.505 ENSMUST00000168740.1
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_+_117266216 0.502 ENSMUST00000019038.8
 Sept9
septin 9
chr8_-_115707778 0.478 ENSMUST00000109104.1
 Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr4_+_109343029 0.447 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chrX_+_159459125 0.444 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
 Map7d2


MAP7 domain containing 2


chr11_-_102819663 0.442 ENSMUST00000092567.4
 Gjc1
gap junction protein, gamma 1
chr3_+_107595031 0.422 ENSMUST00000014747.1
 Alx3
aristaless-like homeobox 3
chr18_+_23753708 0.418 ENSMUST00000115830.1
 Mapre2
microtubule-associated protein, RP/EB family, member 2
chr11_+_70018421 0.400 ENSMUST00000108588.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr7_+_128246812 0.360 ENSMUST00000164710.1
ENSMUST00000070656.5
 Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr2_-_32424005 0.359 ENSMUST00000113307.2
 Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr11_+_23666007 0.351 ENSMUST00000058163.4
 Pus10
pseudouridylate synthase 10
chr7_-_127615208 0.334 ENSMUST00000122066.1
 Zfp629
zinc finger protein 629
chr7_+_128246953 0.330 ENSMUST00000167965.1
 Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr2_-_125723387 0.326 ENSMUST00000042246.7
 Shc4
SHC (Src homology 2 domain containing) family, member 4
chr2_+_3118335 0.311 ENSMUST00000115099.2
 Fam171a1
family with sequence similarity 171, member A1
chr7_-_127615226 0.302 ENSMUST00000084564.3
 Zfp629
zinc finger protein 629
chrX_-_7741288 0.295 ENSMUST00000033490.6
 Ccdc120
coiled-coil domain containing 120
chr2_+_3118407 0.291 ENSMUST00000091505.4
 Fam171a1
family with sequence similarity 171, member A1
chr8_+_111536492 0.282 ENSMUST00000168428.1
ENSMUST00000171182.1
 Znrf1

zinc and ring finger 1

chr19_-_21472552 0.260 ENSMUST00000087600.3
 Gda
guanine deaminase
chr10_-_128498676 0.253 ENSMUST00000026428.3
 Myl6b
myosin, light polypeptide 6B
chr2_+_4882204 0.235 ENSMUST00000115019.1
 Sephs1
selenophosphate synthetase 1
chr8_+_111536793 0.204 ENSMUST00000095176.5
 Znrf1
zinc and ring finger 1
chr7_-_4164442 0.187 ENSMUST00000140410.1
ENSMUST00000143825.1
 Cdc42ep5

CDC42 effector protein (Rho GTPase binding) 5

chr6_-_113501818 0.178 ENSMUST00000101059.1
 Prrt3
proline-rich transmembrane protein 3
chr14_-_54653616 0.165 ENSMUST00000126166.1
ENSMUST00000141453.1
ENSMUST00000150371.1
ENSMUST00000123875.1
ENSMUST00000022794.7
ENSMUST00000148754.3
 Acin1





apoptotic chromatin condensation inducer 1





chr7_+_128237357 0.156 ENSMUST00000044660.5
 Armc5
armadillo repeat containing 5
chr7_-_4164796 0.139 ENSMUST00000076831.6
 Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr17_-_27728889 0.129 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
 Spdef



SAM pointed domain containing ets transcription factor



chr1_+_143640664 0.123 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_+_4690604 0.121 ENSMUST00000120836.1
 Brsk1
BR serine/threonine kinase 1
chrX_+_13071500 0.103 ENSMUST00000089302.4
 Usp9x
ubiquitin specific peptidase 9, X chromosome
chr2_+_167777467 0.096 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr7_+_4690760 0.086 ENSMUST00000048248.7
 Brsk1
BR serine/threonine kinase 1
chr11_-_23665862 0.059 ENSMUST00000020523.3
 Pex13
peroxisomal biogenesis factor 13
chr16_-_29541483 0.053 ENSMUST00000057018.8
ENSMUST00000182627.1
 Atp13a4

ATPase type 13A4

chr15_-_76199835 0.047 ENSMUST00000054449.7
ENSMUST00000169714.1
ENSMUST00000165453.1
 Plec


plectin


chr17_+_69383319 0.032 ENSMUST00000062369.7
 Zbtb14
zinc finger and BTB domain containing 14
chr17_+_69383024 0.024 ENSMUST00000112674.1
 Zbtb14
zinc finger and BTB domain containing 14
chr16_+_30065333 0.022 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr6_-_85502980 0.014 ENSMUST00000159062.1
 Fbxo41
F-box protein 41
chr3_-_79145875 0.011 ENSMUST00000118340.1
 Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr11_-_118569910 0.005 ENSMUST00000136551.1
 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.0 12.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.7 3.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 2.0 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.6 1.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.6 1.7 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.3 1.7 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.3 1.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.2 0.7 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.6 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) motor learning(GO:0061743) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 1.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 0.6 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
0.2 0.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.7 GO:0060032 notochord regression(GO:0060032)
0.2 1.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 1.4 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.6 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 1.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.3 GO:0046098 purine nucleobase catabolic process(GO:0006145) guanine metabolic process(GO:0046098)
0.1 0.9 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 1.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 1.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.9 GO:0031103 axon regeneration(GO:0031103)
0.0 0.3 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.4 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.0 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 12.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 6.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.5 1.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 12.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 2.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 1.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 6.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 1.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.2 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.1 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 2.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.3 GO:0030552 cAMP binding(GO:0030552)
0.0 1.7 GO:0043621 protein self-association(GO:0043621)
0.0 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)