Motif ID: Zscan4c

Z-value: 0.572


Transcription factors associated with Zscan4c:

Gene SymbolEntrez IDGene Name
Zscan4c ENSMUSG00000054272.5 Zscan4c



Activity profile for motif Zscan4c.

activity profile for motif Zscan4c


Sorted Z-values histogram for motif Zscan4c

Sorted Z-values for motif Zscan4c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zscan4c

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_107760221 1.901 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr7_+_130936172 1.743 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr4_-_46991842 1.391 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_-_78718113 1.114 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr9_+_89909775 0.993 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr16_+_45094036 0.953 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chr2_-_36105271 0.944 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr17_+_78508063 0.921 ENSMUST00000024880.9
 Vit
vitrin
chr11_-_101785252 0.855 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr5_+_114896936 0.839 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
 Oasl2


2'-5' oligoadenylate synthetase-like 2


chr10_-_42276688 0.821 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr15_-_37458523 0.808 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr9_-_44799179 0.737 ENSMUST00000114705.1
ENSMUST00000002100.7
 Tmem25

transmembrane protein 25

chr5_+_64970069 0.603 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr9_-_49798905 0.569 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chr3_-_108017806 0.535 ENSMUST00000126593.1
 Gstm1
glutathione S-transferase, mu 1
chr2_+_102659213 0.515 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_+_26733845 0.507 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr16_-_37384940 0.497 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr10_-_42276744 0.489 ENSMUST00000105502.1
ENSMUST00000105501.1
 Foxo3

forkhead box O3

chr9_+_26733728 0.483 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
 B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr2_-_116064512 0.473 ENSMUST00000074285.6
 Meis2
Meis homeobox 2
chr5_-_44799643 0.471 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr9_+_57940104 0.465 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr10_+_43579161 0.463 ENSMUST00000058714.8
 Cd24a
CD24a antigen
chr4_+_49059256 0.455 ENSMUST00000076670.2
 E130309F12Rik
RIKEN cDNA E130309F12 gene
chr4_-_87806296 0.453 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr13_+_58807884 0.437 ENSMUST00000079828.5
 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr1_+_132191436 0.416 ENSMUST00000112357.2
 Lemd1
LEM domain containing 1
chr2_+_57238297 0.413 ENSMUST00000112618.2
ENSMUST00000028167.2
 Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr2_-_116064721 0.412 ENSMUST00000110906.2
 Meis2
Meis homeobox 2
chr7_-_98178254 0.404 ENSMUST00000040971.7
 Capn5
calpain 5
chr2_-_116065047 0.403 ENSMUST00000028639.6
ENSMUST00000102538.4
 Meis2

Meis homeobox 2

chr2_-_63184253 0.395 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr19_+_8664005 0.376 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr2_+_106695594 0.375 ENSMUST00000016530.7
 Mpped2
metallophosphoesterase domain containing 2
chr9_-_49798729 0.373 ENSMUST00000166811.2
 Ncam1
neural cell adhesion molecule 1
chr18_-_79109391 0.369 ENSMUST00000025430.8
ENSMUST00000161465.2
 Setbp1

SET binding protein 1

chr4_-_87806276 0.363 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_+_28963892 0.329 ENSMUST00000045674.2
 Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr7_+_46841475 0.325 ENSMUST00000147535.1
 Ldha
lactate dehydrogenase A
chr9_-_50739365 0.319 ENSMUST00000117093.1
ENSMUST00000121634.1
 Dixdc1

DIX domain containing 1

chr2_+_30364262 0.318 ENSMUST00000142801.1
ENSMUST00000100214.3
 Fam73b

family with sequence similarity 73, member B

chr6_-_122340200 0.315 ENSMUST00000159384.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr11_+_16257706 0.311 ENSMUST00000109645.2
ENSMUST00000109647.2
 Vstm2a

V-set and transmembrane domain containing 2A

chr10_+_81292961 0.305 ENSMUST00000163075.1
ENSMUST00000105327.3
ENSMUST00000045469.8
 Pip5k1c


phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma


chr2_+_30364227 0.304 ENSMUST00000077977.7
ENSMUST00000140075.2
 Fam73b

family with sequence similarity 73, member B

chr15_+_80173642 0.288 ENSMUST00000044970.6
 Mgat3
mannoside acetylglucosaminyltransferase 3
chr7_-_47132698 0.278 ENSMUST00000033142.5
 Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr10_-_78295394 0.272 ENSMUST00000105387.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_70237638 0.247 ENSMUST00000100950.3
 0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr18_-_23041641 0.239 ENSMUST00000097651.3
 Nol4
nucleolar protein 4
chr16_-_38713235 0.232 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr14_-_60177482 0.231 ENSMUST00000140924.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr6_-_122340499 0.228 ENSMUST00000160843.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr4_-_116464151 0.209 ENSMUST00000106486.1
ENSMUST00000106485.1
 Mast2

microtubule associated serine/threonine kinase 2

chr11_-_70237761 0.207 ENSMUST00000108576.3
 0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr4_+_123183722 0.204 ENSMUST00000152194.1
 Hpcal4
hippocalcin-like 4
chr9_+_36832684 0.189 ENSMUST00000034630.8
 Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr11_-_70237886 0.176 ENSMUST00000108577.1
ENSMUST00000108579.1
ENSMUST00000021181.6
ENSMUST00000108578.2
ENSMUST00000102569.3
 0610010K14Rik




RIKEN cDNA 0610010K14 gene




chr10_+_118860826 0.172 ENSMUST00000059966.4
 4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr16_+_4756845 0.168 ENSMUST00000140367.1
ENSMUST00000118885.1
ENSMUST00000121529.1
 Hmox2


heme oxygenase (decycling) 2


chr5_-_145201829 0.164 ENSMUST00000162220.1
ENSMUST00000031632.8
 Zkscan14

zinc finger with KRAB and SCAN domains 14

chr2_-_91182848 0.139 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
 Madd


MAP-kinase activating death domain


chr7_-_98361275 0.127 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
 Tsku


tsukushi


chr11_-_70237852 0.121 ENSMUST00000108575.2
 0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr15_-_79403248 0.112 ENSMUST00000074991.2
 Tmem184b
transmembrane protein 184b
chr19_-_28963863 0.096 ENSMUST00000161813.1
 4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_-_158146385 0.093 ENSMUST00000103122.3
 Tgm2
transglutaminase 2, C polypeptide
chr8_-_95142477 0.090 ENSMUST00000034240.7
ENSMUST00000169748.1
 Kifc3

kinesin family member C3

chr8_-_48555846 0.090 ENSMUST00000110345.1
ENSMUST00000110343.1
 Tenm3

teneurin transmembrane protein 3

chr11_-_109473220 0.087 ENSMUST00000070872.6
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chrX_+_56731779 0.077 ENSMUST00000023854.3
ENSMUST00000114769.2
 Fhl1

four and a half LIM domains 1

chr9_+_21936986 0.072 ENSMUST00000046371.6
 BC018242
cDNA sequence BC018242
chr2_+_68861564 0.067 ENSMUST00000176018.1
 Cers6
ceramide synthase 6
chr3_-_51277470 0.064 ENSMUST00000108053.2
ENSMUST00000108051.1
 Elf2

E74-like factor 2

chr16_-_78576649 0.063 ENSMUST00000114220.1
ENSMUST00000114219.1
ENSMUST00000114218.1
 D16Ertd472e


DNA segment, Chr 16, ERATO Doi 472, expressed


chr6_-_122340525 0.063 ENSMUST00000112600.2
 Phc1
polyhomeotic-like 1 (Drosophila)
chr13_-_56296551 0.059 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr18_-_39489776 0.059 ENSMUST00000025300.6
 Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr16_-_9994921 0.056 ENSMUST00000115835.1
 Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr4_-_117496940 0.055 ENSMUST00000030439.8
 Rnf220
ring finger protein 220
chr11_-_109473598 0.053 ENSMUST00000070152.5
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr1_+_74375203 0.050 ENSMUST00000027368.5
 Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr6_-_55681257 0.050 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr19_-_28680077 0.042 ENSMUST00000162022.1
ENSMUST00000112612.2
 Glis3

GLIS family zinc finger 3

chr10_-_58225706 0.028 ENSMUST00000174056.1
 AW822073
expressed sequence AW822073
chr6_+_48593927 0.018 ENSMUST00000135151.1
 Repin1
replication initiator 1
chr12_-_69892989 0.006 ENSMUST00000110567.1
ENSMUST00000171211.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr8_+_82863351 0.006 ENSMUST00000078525.5
 Rnf150
ring finger protein 150
chr18_-_40219324 0.003 ENSMUST00000025364.4
 Yipf5
Yip1 domain family, member 5
chr19_-_21472552 0.002 ENSMUST00000087600.3
 Gda
guanine deaminase
chr19_+_53310495 0.002 ENSMUST00000003870.7
 Mxi1
Max interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 0.9 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 1.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 1.3 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.2 0.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.5 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.8 GO:0007379 segment specification(GO:0007379)
0.1 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 1.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.3 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0035690 cellular response to drug(GO:0035690)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 1.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 0.6 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.1 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)