Motif ID: Egr4

Z-value: 0.637


Transcription factors associated with Egr4:

Gene SymbolEntrez IDGene Name
Egr4 ENSMUSG00000071341.3 Egr4



Activity profile for motif Egr4.

activity profile for motif Egr4


Sorted Z-values histogram for motif Egr4

Sorted Z-values for motif Egr4



Network of associatons between targets according to the STRING database.



First level regulatory network of Egr4

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_19018956 1.886 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
 Meis1


Meis homeobox 1


chr11_-_19018714 1.556 ENSMUST00000177417.1
 Meis1
Meis homeobox 1
chrX_+_36195968 1.555 ENSMUST00000115256.1
 Zcchc12
zinc finger, CCHC domain containing 12
chr7_+_35119285 1.448 ENSMUST00000042985.9
 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr5_+_137288273 1.340 ENSMUST00000024099.4
ENSMUST00000085934.3
 Ache

acetylcholinesterase

chr4_+_128883549 1.327 ENSMUST00000035667.8
 Trim62
tripartite motif-containing 62
chr19_-_50678642 1.283 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chrX_+_36195938 1.267 ENSMUST00000048067.3
 Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195950 1.258 ENSMUST00000115257.1
 Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195904 1.247 ENSMUST00000115258.2
 Zcchc12
zinc finger, CCHC domain containing 12
chr6_+_4747306 1.202 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
 Peg10


paternally expressed 10


chr17_-_70851189 1.160 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr18_+_35829798 1.144 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr13_+_48261427 1.050 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr12_+_17690793 1.045 ENSMUST00000071858.3
 Hpcal1
hippocalcin-like 1
chr19_+_25505618 0.982 ENSMUST00000025755.4
 Dmrt1
doublesex and mab-3 related transcription factor 1
chr19_-_5085483 0.965 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
 Tmem151a


transmembrane protein 151A


chr14_+_84443553 0.867 ENSMUST00000071370.5
 Pcdh17
protocadherin 17
chr18_+_86394952 0.810 ENSMUST00000058829.2
 Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr14_+_56668242 0.807 ENSMUST00000116468.1
 Mphosph8
M-phase phosphoprotein 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.3 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 3.4 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.4 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.3 1.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.0 GO:0060903 negative regulation of meiotic nuclear division(GO:0045835) positive regulation of meiosis I(GO:0060903)
0.1 0.9 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.8 GO:2000463 receptor localization to synapse(GO:0097120) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.4 GO:0003100 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of systemic arterial blood pressure by endothelin(GO:0003100) beta selection(GO:0043366)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.2 GO:0016607 nuclear speck(GO:0016607)
0.5 1.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.3 GO:0032183 SUMO binding(GO:0032183)
0.0 3.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.3 1.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)