Motif ID: Lhx3

Z-value: 0.610


Transcription factors associated with Lhx3:

Gene SymbolEntrez IDGene Name
Lhx3 ENSMUSG00000026934.9 Lhx3



Activity profile for motif Lhx3.

activity profile for motif Lhx3


Sorted Z-values histogram for motif Lhx3

Sorted Z-values for motif Lhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 85 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_45103747 3.041 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr7_-_103827922 2.858 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr4_+_136143497 2.731 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr13_+_49608030 2.230 ENSMUST00000021822.5
 Ogn
osteoglycin
chr4_+_118961578 2.177 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr18_+_57468478 2.074 ENSMUST00000091892.2
 Ctxn3
cortexin 3
chr3_+_151437887 1.994 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr14_+_80000292 1.763 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr11_+_109543694 1.472 ENSMUST00000106696.1
 Arsg
arylsulfatase G
chr8_-_21906412 1.381 ENSMUST00000051965.4
 Defb11
defensin beta 11
chr1_+_177444653 1.257 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr2_-_160619971 1.220 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chrX_+_66653003 1.173 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr5_-_70842617 0.988 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_-_33086366 0.976 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr10_-_62507737 0.952 ENSMUST00000020271.6
 Srgn
serglycin
chr4_-_14621805 0.944 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr13_-_101692624 0.940 ENSMUST00000035532.6
 Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr2_-_33087169 0.924 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr5_-_62766153 0.895 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 2.7 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 2.2 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.4 GO:0042742 defense response to bacterium(GO:0042742)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.9 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.7 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 0.5 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 3.0 GO:0019770 IgG receptor activity(GO:0019770)
0.7 2.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.7 2.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 2.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 1.8 GO:0045296 cadherin binding(GO:0045296)
0.2 1.5 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.0 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)
0.2 0.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)