Motif ID: Lhx3
Z-value: 0.610
Transcription factors associated with Lhx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Lhx3 | ENSMUSG00000026934.9 | Lhx3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.2 | 0.7 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.2 | 0.5 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.1 | 0.6 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.0 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.5 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
0.1 | 0.7 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.1 | 0.7 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 0.5 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.1 | 2.7 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.1 | 0.9 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.1 | 0.4 | GO:0014012 | negative regulation of Schwann cell proliferation(GO:0010626) peripheral nervous system axon regeneration(GO:0014012) |
0.1 | 0.4 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 0.6 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 0.3 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.1 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 1.8 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 1.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 2.2 | GO:0009063 | cellular amino acid catabolic process(GO:0009063) |
0.0 | 1.1 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 3.0 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.6 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.1 | GO:0033762 | response to glucagon(GO:0033762) |
0.0 | 0.4 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.1 | GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
0.0 | 0.1 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.0 | 0.5 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.0 | 1.4 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.0 | 0.4 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.0 | 0.6 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 0.2 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.9 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.1 | 0.6 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 1.8 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.0 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 1.0 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 0.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 1.3 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.2 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 1.3 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.1 | GO:0071439 | clathrin complex(GO:0071439) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.7 | 2.2 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.7 | 2.9 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
0.2 | 0.9 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.2 | 1.5 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
0.1 | 0.5 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.1 | 0.7 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.1 | 0.6 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.7 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 1.0 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 0.6 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 1.0 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.1 | 2.2 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 1.8 | GO:0045296 | cadherin binding(GO:0045296) |
0.0 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.5 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 2.2 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.4 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.0 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.0 | 0.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.5 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 0.1 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |