Motif ID: Zfp219_Zfp740

Z-value: 1.554

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp219mm10_v2_chr14_-_52020698_520207370.658.1e-04Click!
Zfp740mm10_v2_chr15_+_102203639_1022037090.252.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_134747241 8.775 ENSMUST00000015138.9
Eln
elastin
chr7_-_78577771 7.386 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_78578308 7.099 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_56972437 6.701 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr15_+_57694651 6.389 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr16_+_44173271 5.089 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr16_+_43503607 4.740 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr11_-_69369377 4.474 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr4_-_88033328 4.433 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_180225812 4.310 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr2_-_116065798 4.263 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr16_+_44173239 4.151 ENSMUST00000119746.1
Gm608
predicted gene 608
chr4_+_144892813 3.866 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr10_-_127341583 3.644 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr10_-_127620922 3.579 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr17_+_75005523 3.529 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr3_+_28263563 3.509 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr6_+_4903350 3.218 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr4_+_144893077 3.155 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr10_-_127620960 3.155 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.8 14.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.7 10.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 7.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
1.5 7.4 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.6 6.8 GO:0042572 retinol metabolic process(GO:0042572)
0.3 6.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 6.2 GO:0006402 mRNA catabolic process(GO:0006402)
0.1 5.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
1.1 5.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.9 5.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.6 5.4 GO:0042118 endothelial cell activation(GO:0042118)
1.8 5.3 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 5.2 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.5 5.0 GO:0007379 segment specification(GO:0007379)
0.3 4.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 4.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 4.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6 4.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 4.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.9 3.6 GO:0060032 notochord regression(GO:0060032)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 10.0 GO:0005905 clathrin-coated pit(GO:0005905)
2.9 8.8 GO:0071953 elastic fiber(GO:0071953)
0.1 7.2 GO:0055037 recycling endosome(GO:0055037)
0.0 6.4 GO:0043235 receptor complex(GO:0043235)
1.1 5.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 4.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 4.7 GO:0035869 ciliary transition zone(GO:0035869)
1.1 4.3 GO:0043259 laminin-10 complex(GO:0043259)
0.3 3.6 GO:0097542 ciliary tip(GO:0097542)
1.2 3.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 3.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 3.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.9 GO:0097449 astrocyte projection(GO:0097449)
0.2 2.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.6 2.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.7 2.6 GO:0043511 inhibin complex(GO:0043511)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 14.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 10.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 8.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 7.4 GO:0034185 apolipoprotein binding(GO:0034185)
1.0 6.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.3 6.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.2 5.6 GO:0070412 R-SMAD binding(GO:0070412)
0.3 5.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 5.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 5.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 4.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 4.7 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.3 4.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 4.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 4.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 4.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.9 3.5 GO:0050436 microfibril binding(GO:0050436)
0.1 3.0 GO:0004402 histone acetyltransferase activity(GO:0004402)