Motif ID: Scrt2
Z-value: 0.869
Transcription factors associated with Scrt2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Scrt2 | ENSMUSG00000060257.2 | Scrt2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Scrt2 | mm10_v2_chr2_+_152081529_152081624 | -0.20 | 3.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.6 | GO:0072034 | renal vesicle induction(GO:0072034) |
| 1.1 | 3.2 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.6 | 3.0 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.5 | 1.4 | GO:2000564 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 0.3 | 1.0 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.3 | 2.1 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.3 | 1.1 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.3 | 1.7 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.3 | 0.8 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.2 | 1.0 | GO:0015819 | lysine transport(GO:0015819) |
| 0.2 | 4.5 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) |
| 0.2 | 1.1 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 0.5 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.1 | 1.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 0.4 | GO:0035696 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.1 | 0.6 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.1 | 2.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 3.4 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 1.2 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.1 | 0.8 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.1 | 0.4 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.1 | 0.2 | GO:0048239 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.1 | 0.3 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 1.5 | GO:0008105 | asymmetric protein localization(GO:0008105) |
| 0.1 | 0.3 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.1 | 0.3 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 0.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 1.1 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 0.3 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 1.0 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.2 | GO:0002024 | diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845) |
| 0.0 | 0.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.4 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 1.3 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.5 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.0 | 0.5 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.4 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 1.1 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 0.9 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.0 | 0.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.1 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.3 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
| 0.0 | 0.3 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 0.1 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.0 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.9 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 1.1 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 0.3 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.9 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 1.0 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 1.7 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 2.3 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.3 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 0.2 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.8 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 2.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.6 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.4 | 1.1 | GO:0019002 | GMP binding(GO:0019002) |
| 0.3 | 3.9 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.2 | 2.4 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.2 | 0.8 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.1 | 1.0 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
| 0.1 | 0.6 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.1 | 0.3 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.1 | 1.9 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 1.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 3.6 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.1 | 0.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 1.0 | GO:0017166 | dystroglycan binding(GO:0002162) vinculin binding(GO:0017166) |
| 0.0 | 3.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 1.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 3.6 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.3 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 1.1 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 1.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.4 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.2 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 0.3 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 1.1 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.2 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 0.3 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.5 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
