Motif ID: Scrt2

Z-value: 0.869


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.203.6e-01Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Showing 1 to 20 of 104 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_57008187 3.877 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr17_-_25570678 3.577 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr16_+_42907563 3.380 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr9_+_45370185 3.283 ENSMUST00000085939.6
 Fxyd6
FXYD domain-containing ion transport regulator 6
chr18_-_82406777 3.190 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr5_+_118169712 3.043 ENSMUST00000054836.6
 Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr3_-_53657339 2.457 ENSMUST00000091137.4
 Frem2
Fras1 related extracellular matrix protein 2
chr7_+_81523531 2.199 ENSMUST00000181903.1
 2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr3_+_34649987 2.145 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr11_-_55419898 2.000 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr12_-_4592927 1.949 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr3_+_130180882 1.683 ENSMUST00000106353.1
ENSMUST00000080335.4
 Col25a1

collagen, type XXV, alpha 1

chr7_+_81523555 1.668 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
 2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr11_+_53770458 1.447 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr7_+_126847908 1.374 ENSMUST00000147257.1
ENSMUST00000139174.1
 Doc2a

double C2, alpha

chr3_-_122984404 1.364 ENSMUST00000090379.2
 Usp53
ubiquitin specific peptidase 53
chr2_+_91257323 1.207 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr2_+_91256813 1.191 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
 Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr4_-_151044564 1.184 ENSMUST00000103204.4
 Per3
period circadian clock 3
chr8_-_71537402 1.144 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
1.2 3.6 GO:0072034 renal vesicle induction(GO:0072034)
0.1 3.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 3.2 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.6 3.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 2.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 2.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 1.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.5 GO:0008105 asymmetric protein localization(GO:0008105)
0.5 1.4 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 1.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 1.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.3 1.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.2 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 1.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 1.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.0 GO:0015819 lysine transport(GO:0015819)
0.0 1.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.5 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.1 1.1 GO:0000243 commitment complex(GO:0000243)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.1 0.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 3.3 GO:0005518 collagen binding(GO:0005518)
1.1 3.2 GO:0004966 galanin receptor activity(GO:0004966)
0.2 2.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.9 GO:0035198 miRNA binding(GO:0035198)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.4 1.1 GO:0019002 GMP binding(GO:0019002)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.0 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.0 GO:0017166 dystroglycan binding(GO:0002162) vinculin binding(GO:0017166)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)