Motif ID: Irf3
Z-value: 1.028
Transcription factors associated with Irf3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Irf3 | ENSMUSG00000003184.8 | Irf3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irf3 | mm10_v2_chr7_+_44997648_44997700 | -0.27 | 2.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 71 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.4 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.3 | 4.5 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.1 | 3.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.5 | 3.8 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 0.9 | 3.6 | GO:0009597 | detection of virus(GO:0009597) |
| 0.0 | 3.3 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.6 | 3.1 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.0 | 2.0 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
| 0.3 | 1.5 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 0.3 | 1.4 | GO:0042228 | interleukin-8 biosynthetic process(GO:0042228) |
| 0.2 | 1.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 1.1 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
| 0.1 | 1.0 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 0.7 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 0.7 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.0 | 0.7 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.2 | 0.6 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.2 | 0.5 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 0.1 | 0.5 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.1 | 0.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
Gene overrepresentation in cellular_component category:
Showing 1 to 15 of 15 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.3 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.0 | 4.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.3 | 3.9 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.0 | 3.8 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 3.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.3 | 3.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 1.8 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.4 | 1.2 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.0 | 1.2 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.3 | 1.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 0.5 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 0.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 0.3 | GO:1990462 | omegasome(GO:1990462) |
| 0.0 | 0.2 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 25 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | GO:0005525 | GTP binding(GO:0005525) |
| 0.3 | 6.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.3 | 4.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 4.1 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 1.0 | 3.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 3.6 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 2.0 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.8 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.4 | 1.5 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.0 | 1.4 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.2 | 1.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 1.2 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 1.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.8 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 0.7 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.1 | 0.7 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 0.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 0.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.2 | 0.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
