Motif ID: Atoh1_Bhlhe23

Z-value: 0.460

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_180776749-0.434.0e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_43235856 2.054 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr17_-_6449571 1.509 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_177444653 1.376 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr4_-_82850721 1.236 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr1_+_42697146 1.148 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr5_+_3343893 1.046 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr9_+_72985504 0.989 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chr17_+_88626549 0.975 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chr1_+_15287259 0.933 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr13_-_97747399 0.926 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_+_72985568 0.870 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1


chr13_-_97747373 0.837 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_+_43510267 0.834 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr17_+_88626569 0.794 ENSMUST00000150023.1
Ston1
stonin 1
chr3_-_84259812 0.756 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr14_+_28511344 0.723 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr5_+_129096740 0.715 ENSMUST00000056617.7
ENSMUST00000156437.1
Gpr133

G protein-coupled receptor 133

chr6_+_112273758 0.711 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr9_-_21918089 0.643 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chr2_-_29253001 0.619 ENSMUST00000071201.4
Ntng2
netrin G2
chr11_-_69602741 0.593 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_150323702 0.576 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr15_-_91191733 0.546 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr11_-_35980473 0.520 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr3_+_138065052 0.509 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr2_+_59612034 0.493 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr1_+_177445660 0.455 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr1_-_111864869 0.421 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chr3_-_126998408 0.400 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chrX_+_159708593 0.392 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_155232710 0.382 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr11_+_73160403 0.366 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr9_-_71896047 0.355 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr10_+_69706326 0.334 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr5_+_124194894 0.330 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr1_-_150392719 0.330 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr15_+_25622525 0.309 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr2_-_79456750 0.303 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr6_-_148831395 0.285 ENSMUST00000145960.1
Ipo8
importin 8
chr17_-_35074485 0.273 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr2_+_69670100 0.249 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr8_+_94838321 0.246 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr19_+_7268296 0.219 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr8_+_25602236 0.210 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)


chr2_+_155382186 0.209 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chrX_+_36328353 0.204 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr18_+_77185979 0.203 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr10_-_12923075 0.201 ENSMUST00000180529.1
B230208H11Rik
RIKEN cDNA B230208H11 gene
chr5_-_66618636 0.201 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr8_+_25601591 0.175 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr11_-_98329641 0.171 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr17_-_6827990 0.166 ENSMUST00000181895.1
Gm2885
predicted gene 2885
chr1_-_52800371 0.158 ENSMUST00000159725.1
Inpp1
inositol polyphosphate-1-phosphatase
chrX_+_56454871 0.157 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr2_-_39065505 0.154 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr2_-_39065438 0.150 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr11_+_108920342 0.148 ENSMUST00000052915.7
Axin2
axin2
chr6_-_83033422 0.139 ENSMUST00000089651.5
Dok1
docking protein 1
chr16_+_11008898 0.137 ENSMUST00000180624.1
Gm4262
predicted gene 4262
chr7_+_101394361 0.134 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr6_+_17743582 0.131 ENSMUST00000000674.6
ENSMUST00000077080.2
St7

suppression of tumorigenicity 7

chr10_-_22149270 0.115 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr18_+_34759551 0.109 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C
chr2_-_52558539 0.108 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr7_+_127904079 0.104 ENSMUST00000071056.7
Bckdk
branched chain ketoacid dehydrogenase kinase
chr10_+_59879617 0.101 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr11_+_120232921 0.098 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr14_-_16249675 0.096 ENSMUST00000022311.4
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr4_-_41870612 0.095 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr5_-_124187150 0.092 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_58954675 0.092 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr8_+_4243264 0.088 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr1_+_150392794 0.088 ENSMUST00000124973.2
Tpr
translocated promoter region
chr9_-_26999491 0.086 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chr5_-_66618752 0.084 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr15_-_76918010 0.084 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr2_-_105399286 0.076 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr5_-_144223516 0.076 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr6_+_90462562 0.071 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr3_-_107333289 0.070 ENSMUST00000061772.9
Rbm15
RNA binding motif protein 15
chr16_-_57292845 0.068 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
Tmem30c


transmembrane protein 30C


chr2_-_121807024 0.065 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr14_-_62454793 0.061 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr15_+_30172570 0.060 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr2_+_164833841 0.057 ENSMUST00000152721.1
Ctsa
cathepsin A
chr6_+_83034173 0.053 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr11_-_87404380 0.053 ENSMUST00000067692.6
Rad51c
RAD51 homolog C
chr11_+_31872100 0.050 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr19_-_53371766 0.049 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr15_+_82256023 0.046 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr17_+_82539258 0.040 ENSMUST00000097278.3
Gm6594
predicted pseudogene 6594
chr2_+_62046580 0.035 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr19_-_37207293 0.034 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr2_+_65930117 0.032 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr11_+_49247462 0.025 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr16_-_17722879 0.025 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr15_+_78913916 0.024 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chrX_+_56786527 0.023 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr10_+_59879556 0.023 ENSMUST00000147914.1
ENSMUST00000146590.1
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr2_+_127587214 0.018 ENSMUST00000028852.6
Mrps5
mitochondrial ribosomal protein S5
chr2_+_62046462 0.012 ENSMUST00000102735.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr18_+_55057557 0.006 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr2_+_62046623 0.005 ENSMUST00000112480.2
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.1 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 1.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.7 GO:1900020 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.6 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 2.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:2000054 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.5 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.9 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.8 GO:0021766 hippocampus development(GO:0021766)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)