Motif ID: Atoh1_Bhlhe23

Z-value: 0.460

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_180776749-0.434.0e-02Click!


Activity profile for motif Atoh1_Bhlhe23.

activity profile for motif Atoh1_Bhlhe23


Sorted Z-values histogram for motif Atoh1_Bhlhe23

Sorted Z-values for motif Atoh1_Bhlhe23



Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Showing 1 to 20 of 103 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_43235856 2.054 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr17_-_6449571 1.509 ENSMUST00000180035.1
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_177444653 1.376 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr4_-_82850721 1.236 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr1_+_42697146 1.148 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr5_+_3343893 1.046 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr9_+_72985504 0.989 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr17_+_88626549 0.975 ENSMUST00000163588.1
ENSMUST00000064035.6
 Ston1

stonin 1

chr1_+_15287259 0.933 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr13_-_97747399 0.926 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_+_72985568 0.870 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr13_-_97747373 0.837 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_+_43510267 0.834 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr17_+_88626569 0.794 ENSMUST00000150023.1
 Ston1
stonin 1
chr3_-_84259812 0.756 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr14_+_28511344 0.723 ENSMUST00000112272.1
 Wnt5a
wingless-related MMTV integration site 5A
chr5_+_129096740 0.715 ENSMUST00000056617.7
ENSMUST00000156437.1
 Gpr133

G protein-coupled receptor 133

chr6_+_112273758 0.711 ENSMUST00000032376.5
 Lmcd1
LIM and cysteine-rich domains 1
chr9_-_21918089 0.643 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr2_-_29253001 0.619 ENSMUST00000071201.4
 Ntng2
netrin G2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 1.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.8 GO:0021766 hippocampus development(GO:0021766)
0.1 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 1.1 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 1.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.9 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 0.7 GO:1900020 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.5 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)