Motif ID: Tfdp1_Wt1_Egr2

Z-value: 1.971

Transcription factors associated with Tfdp1_Wt1_Egr2:

Gene SymbolEntrez IDGene Name
Egr2 ENSMUSG00000037868.9 Egr2
Tfdp1 ENSMUSG00000038482.10 Tfdp1
Wt1 ENSMUSG00000016458.7 Wt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfdp1mm10_v2_chr8_+_13339656_133396740.521.1e-02Click!
Egr2mm10_v2_chr10_+_67537861_67537930-0.125.9e-01Click!


Activity profile for motif Tfdp1_Wt1_Egr2.

activity profile for motif Tfdp1_Wt1_Egr2


Sorted Z-values histogram for motif Tfdp1_Wt1_Egr2

Sorted Z-values for motif Tfdp1_Wt1_Egr2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfdp1_Wt1_Egr2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22163299 12.088 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr7_-_34812677 11.849 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr13_-_56252163 9.989 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr3_-_8667033 9.915 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr6_-_115994953 8.495 ENSMUST00000015511.8
 Plxnd1
plexin D1
chr4_+_125490688 8.303 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr11_+_7063423 7.753 ENSMUST00000020706.4
 Adcy1
adenylate cyclase 1
chr9_-_97018823 7.478 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr12_+_112146187 7.154 ENSMUST00000128402.2
 Kif26a
kinesin family member 26A
chr1_+_167001457 6.995 ENSMUST00000126198.1
 Fam78b
family with sequence similarity 78, member B
chr1_+_167001417 6.830 ENSMUST00000165874.1
 Fam78b
family with sequence similarity 78, member B
chr7_-_126082406 6.822 ENSMUST00000073935.5
 Gsg1l
GSG1-like
chr11_-_95587691 6.743 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr19_+_47178820 6.591 ENSMUST00000111808.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr9_+_107400043 6.353 ENSMUST00000166799.1
ENSMUST00000170737.1
 Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr5_+_139543889 6.325 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr4_-_153482768 6.131 ENSMUST00000105646.2
 Ajap1
adherens junction associated protein 1
chr5_-_115194283 6.068 ENSMUST00000112113.1
 Cabp1
calcium binding protein 1
chr15_-_75747922 6.059 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr11_+_119942763 6.019 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
 Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,069 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 21.0 GO:0051028 mRNA transport(GO:0051028)
1.7 18.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
1.5 14.6 GO:0008063 Toll signaling pathway(GO:0008063)
1.0 13.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.9 13.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.7 13.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.1 12.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
3.1 12.3 GO:0003360 brainstem development(GO:0003360)
0.8 11.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
1.3 11.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 11.2 GO:0035690 cellular response to drug(GO:0035690)
2.7 10.8 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.8 10.6 GO:0051764 actin crosslink formation(GO:0051764)
1.5 10.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 10.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.4 9.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 9.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 9.7 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
1.9 9.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
1.3 9.3 GO:0044027 hypermethylation of CpG island(GO:0044027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 384 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 22.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 20.4 GO:0043204 perikaryon(GO:0043204)
1.2 17.7 GO:0043196 varicosity(GO:0043196)
0.1 16.4 GO:0098794 postsynapse(GO:0098794)
0.4 15.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 15.5 GO:0044309 neuron spine(GO:0044309)
1.3 14.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 14.7 GO:0005871 kinesin complex(GO:0005871)
0.2 14.0 GO:0043195 terminal bouton(GO:0043195)
0.2 13.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6 13.0 GO:0001741 XY body(GO:0001741)
0.1 12.7 GO:0000776 kinetochore(GO:0000776)
4.0 12.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 11.9 GO:0005643 nuclear pore(GO:0005643)
0.5 11.8 GO:0071565 nBAF complex(GO:0071565)
0.8 11.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.4 9.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 9.9 GO:0030427 site of polarized growth(GO:0030427)
0.3 9.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 9.0 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 584 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 26.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 24.2 GO:0008017 microtubule binding(GO:0008017)
0.5 20.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.5 19.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.8 18.1 GO:0001784 phosphotyrosine binding(GO:0001784)
1.2 17.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 15.9 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.6 15.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 15.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.6 14.8 GO:0001972 retinoic acid binding(GO:0001972)
0.6 14.7 GO:0070064 proline-rich region binding(GO:0070064)
1.1 13.7 GO:0031996 thioesterase binding(GO:0031996)
2.0 12.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.1 12.2 GO:0048185 activin binding(GO:0048185)
0.2 12.1 GO:0003777 microtubule motor activity(GO:0003777)
3.0 11.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.8 10.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 10.6 GO:0051287 NAD binding(GO:0051287)
0.9 10.4 GO:0030957 Tat protein binding(GO:0030957)
0.6 10.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)