Motif ID: Ascl2

Z-value: 0.631


Transcription factors associated with Ascl2:

Gene SymbolEntrez IDGene Name
Ascl2 ENSMUSG00000009248.5 Ascl2



Activity profile for motif Ascl2.

activity profile for motif Ascl2


Sorted Z-values histogram for motif Ascl2

Sorted Z-values for motif Ascl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ascl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_106458440 3.048 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr8_+_31091593 2.625 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr7_-_28302238 2.566 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr3_-_116253467 2.360 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr12_-_40038025 2.276 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr12_-_40037387 2.147 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr1_-_84696182 1.973 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr5_+_114568016 1.964 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chrX_-_133688978 1.912 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr5_-_69341699 1.812 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr7_-_141443314 1.685 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr9_-_43239816 1.579 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chrX_-_106485214 1.571 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr8_+_105518736 1.534 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr6_-_72235559 1.517 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr8_-_105471481 1.426 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr2_+_136052180 1.412 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr6_+_4755327 1.401 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr13_-_98206151 1.383 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr13_+_24638636 1.380 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 3.0 GO:0001709 cell fate determination(GO:0001709)
0.0 2.9 GO:0051260 protein homooligomerization(GO:0051260)
0.9 2.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.5 2.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 2.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 2.3 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 2.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 2.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.7 GO:0015813 L-glutamate transport(GO:0015813)
0.0 1.7 GO:0031638 zymogen activation(GO:0031638)
0.2 1.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.5 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.1 1.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 1.4 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 1.4 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.1 1.3 GO:0042711 maternal behavior(GO:0042711)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 1.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 0.8 GO:0005940 septin ring(GO:0005940)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.4 GO:0005112 Notch binding(GO:0005112)
0.0 4.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 4.2 GO:0003924 GTPase activity(GO:0003924)
0.0 4.1 GO:0003779 actin binding(GO:0003779)
0.1 2.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.9 2.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.1 1.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.2 GO:0005044 scavenger receptor activity(GO:0005044)