Motif ID: Klf7

Z-value: 0.554


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64122256_64122321-0.511.3e-02Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Showing 1 to 20 of 94 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 2.595 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr12_-_11436607 0.957 ENSMUST00000072299.5
 Vsnl1
visinin-like 1
chr1_-_138847579 0.857 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr5_+_140607334 0.803 ENSMUST00000031555.1
 Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_4592927 0.802 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr5_+_137761680 0.708 ENSMUST00000110983.2
ENSMUST00000031738.4
 Tsc22d4

TSC22 domain family, member 4

chr9_-_32344237 0.660 ENSMUST00000034533.5
 Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr4_-_87230435 0.611 ENSMUST00000107157.2
 Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr5_+_33658123 0.588 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr18_+_67133713 0.570 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr10_+_79682169 0.556 ENSMUST00000020550.5
 Cdc34
cell division cycle 34
chr15_+_99074968 0.527 ENSMUST00000039665.6
 Troap
trophinin associated protein
chrX_+_136270253 0.490 ENSMUST00000178632.1
ENSMUST00000053540.4
 Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr2_+_158375638 0.482 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr13_+_21722057 0.454 ENSMUST00000110476.3
 Hist1h2bm
histone cluster 1, H2bm
chr4_+_152178126 0.401 ENSMUST00000075363.3
 Acot7
acyl-CoA thioesterase 7
chr2_+_119047116 0.392 ENSMUST00000152380.1
ENSMUST00000099542.2
 Casc5

cancer susceptibility candidate 5

chr11_-_70654624 0.387 ENSMUST00000018437.2
 Pfn1
profilin 1
chr7_+_58658181 0.379 ENSMUST00000168747.1
 Atp10a
ATPase, class V, type 10A
chr2_+_172550991 0.373 ENSMUST00000170744.1
 Tfap2c
transcription factor AP-2, gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 1.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 0.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.8 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.8 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.7 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.7 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.5 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 0.4 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.2 0.6 GO:0050827 toxin receptor binding(GO:0050827)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.1 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)