Motif ID: Sox13

Z-value: 0.435


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.341.1e-01Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 4.146 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr7_+_96210107 2.796 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr1_+_19103022 2.487 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr18_+_69593361 1.341 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr8_-_11008458 1.168 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr2_+_25180737 1.141 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr7_-_132813095 0.904 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr12_+_36314160 0.793 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr18_+_64887690 0.671 ENSMUST00000163516.1
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_-_36104060 0.604 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr3_+_34649987 0.587 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr5_-_8367982 0.510 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr1_-_93101825 0.466 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr18_+_37355271 0.465 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr7_-_105787567 0.376 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr7_+_24271568 0.354 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr15_-_50890396 0.345 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr3_+_60501252 0.298 ENSMUST00000099087.2
Mbnl1
muscleblind-like 1 (Drosophila)
chr15_-_91049823 0.236 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
Kif21a




kinesin family member 21A




chr17_-_68004075 0.181 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr10_-_116473418 0.179 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr14_-_47568427 0.178 ENSMUST00000042988.6
Atg14
autophagy related 14
chr11_-_77489666 0.171 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr4_+_103143052 0.160 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr4_+_48585276 0.149 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_-_19001099 0.128 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr7_-_84679346 0.086 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr1_+_39900883 0.084 ENSMUST00000163854.2
ENSMUST00000168431.1
Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr2_+_176236860 0.081 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr9_-_75597643 0.080 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr14_-_121698417 0.076 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr2_-_119662756 0.063 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr17_+_24886643 0.053 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr7_-_121035096 0.044 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chr3_-_96058446 0.039 ENSMUST00000015891.5
Vps45
vacuolar protein sorting 45 (yeast)
chr14_+_79515618 0.038 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr1_+_135729147 0.034 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr1_+_17145357 0.024 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr13_-_66851513 0.022 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr10_-_53647080 0.022 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr19_-_7241216 0.009 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.3 4.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.8 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 1.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 2.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 4.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 4.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)