Motif ID: Ikzf2

Z-value: 0.800


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.087.0e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 4.283 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr15_+_3270767 3.821 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr6_+_4003926 1.190 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr12_+_75308308 1.161 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr11_-_55419898 1.030 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr1_-_45503282 1.015 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr9_-_42944479 0.959 ENSMUST00000114865.1
 Grik4
glutamate receptor, ionotropic, kainate 4
chr5_-_123141067 0.925 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr3_-_116129615 0.908 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr2_-_71546745 0.750 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr14_+_54936456 0.711 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_30913398 0.696 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr13_-_103764502 0.666 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chrX_+_106920618 0.658 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr3_+_159839729 0.651 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr6_+_15185203 0.650 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr19_+_55894508 0.645 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_-_77170592 0.643 ENSMUST00000164114.2
ENSMUST00000049544.7
 Ccdc141

coiled-coil domain containing 141

chr3_+_88214474 0.629 ENSMUST00000181356.1
ENSMUST00000181396.1
 Gm3764

predicted gene 3764

chr1_+_45311538 0.622 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 0.9 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.7 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.7 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.6 GO:0060067 cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.6 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0051642 centrosome localization(GO:0051642)
0.1 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.5 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 0.5 GO:0009404 toxin metabolic process(GO:0009404)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.5 GO:0071953 elastic fiber(GO:0071953)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.8 GO:0008430 selenium binding(GO:0008430)
0.1 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.4 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)