Motif ID: Cxxc1

Z-value: 0.475


Transcription factors associated with Cxxc1:

Gene SymbolEntrez IDGene Name
Cxxc1 ENSMUSG00000024560.6 Cxxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cxxc1mm10_v2_chr18_+_74216118_74216145-0.674.1e-04Click!


Activity profile for motif Cxxc1.

activity profile for motif Cxxc1


Sorted Z-values histogram for motif Cxxc1

Sorted Z-values for motif Cxxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cxxc1

PNG image of the network

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Top targets:


Showing 1 to 20 of 53 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_97415527 2.230 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr7_-_49636847 2.138 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr10_+_50895651 1.677 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr11_-_89302545 1.148 ENSMUST00000061728.3
Nog
noggin
chr5_+_30588078 0.738 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_69921057 0.701 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr11_-_69920892 0.670 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr5_-_4758216 0.629 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr3_-_8964037 0.580 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr10_+_128058974 0.540 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_-_125389177 0.529 ENSMUST00000108707.2
Ubc
ubiquitin C
chr10_+_128058947 0.509 ENSMUST00000052798.7
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr11_-_69920581 0.491 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr10_+_85928491 0.478 ENSMUST00000170396.1
Ascl4
achaete-scute complex homolog 4 (Drosophila)
chr17_-_14203695 0.457 ENSMUST00000053218.5
Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr1_-_124045523 0.435 ENSMUST00000112606.1
Dpp10
dipeptidylpeptidase 10
chr10_-_79766872 0.409 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chrX_-_158043266 0.406 ENSMUST00000026750.8
ENSMUST00000112513.1
Cnksr2

connector enhancer of kinase suppressor of Ras 2

chr11_+_71019593 0.363 ENSMUST00000133413.1
ENSMUST00000164220.1
ENSMUST00000048807.5
Mis12


MIS12 homolog (yeast)


chr8_+_70594466 0.355 ENSMUST00000019283.9
Isyna1
myo-inositol 1-phosphate synthase A1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3 1.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.8 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.5 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.4 GO:0051382 protein localization to kinetochore(GO:0034501) kinetochore assembly(GO:0051382)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.9 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.3 GO:1990047 spindle matrix(GO:1990047)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.1 GO:0019955 cytokine binding(GO:0019955)
0.3 1.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)