Motif ID: Hoxa2

Z-value: 1.144


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 10.704 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr2_-_117342949 6.659 ENSMUST00000102534.4
 Rasgrp1
RAS guanyl releasing protein 1
chr2_-_117342831 6.344 ENSMUST00000178884.1
 Rasgrp1
RAS guanyl releasing protein 1
chr2_-_117342709 6.246 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
 Rasgrp1


RAS guanyl releasing protein 1


chr12_+_109747903 6.157 ENSMUST00000183084.1
ENSMUST00000182300.1
 Mirg

miRNA containing gene

chr14_-_34374617 5.570 ENSMUST00000023826.4
 Sncg
synuclein, gamma
chr10_-_26078987 4.414 ENSMUST00000066049.6
 Tmem200a
transmembrane protein 200A
chr3_+_55782500 4.052 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr8_-_4779513 3.978 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr7_+_45163915 3.463 ENSMUST00000085374.5
 Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr5_+_24985840 3.305 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr9_-_73968901 3.001 ENSMUST00000184666.1
 Unc13c
unc-13 homolog C (C. elegans)
chr8_-_105471481 2.702 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr9_-_106158109 2.497 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr12_+_44328882 2.482 ENSMUST00000020939.8
ENSMUST00000110748.2
 Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr17_-_53539411 2.320 ENSMUST00000056198.3
 Pp2d1
protein phosphatase 2C-like domain containing 1
chr1_-_133907053 2.288 ENSMUST00000149380.1
ENSMUST00000124051.2
 Optc

opticin

chr11_-_58801944 2.271 ENSMUST00000094156.4
ENSMUST00000060581.3
 Fam183b

family with sequence similarity 183, member B

chr6_+_14901344 2.161 ENSMUST00000115477.1
 Foxp2
forkhead box P2
chr19_-_41743665 2.143 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 19.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.5 10.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 5.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 4.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
1.2 3.5 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 3.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 3.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 3.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 2.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 2.8 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 2.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.4 2.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 2.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.7 2.1 GO:1902713 regulation of interferon-gamma secretion(GO:1902713)
0.3 2.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 2.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.9 GO:0007286 spermatid development(GO:0007286)
0.0 1.9 GO:0007050 cell cycle arrest(GO:0007050)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 8.3 GO:0043679 axon terminus(GO:0043679)
0.8 4.6 GO:0031262 Ndc80 complex(GO:0031262)
0.0 4.1 GO:0005635 nuclear envelope(GO:0005635)
0.2 3.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 3.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.6 GO:0005643 nuclear pore(GO:0005643)
0.1 2.5 GO:0043194 axon initial segment(GO:0043194)
0.1 2.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 2.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:1990391 DNA repair complex(GO:1990391)
0.2 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.3 GO:0000805 X chromosome(GO:0000805)
0.0 1.3 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 22.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 5.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.0 GO:0042169 SH2 domain binding(GO:0042169)
1.2 3.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.1 GO:0031005 filamin binding(GO:0031005)
0.2 2.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 2.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 2.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 2.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 2.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.4 2.1 GO:0016936 galactoside binding(GO:0016936)
0.3 2.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 1.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.8 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 1.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)