Motif ID: Hoxa10

Z-value: 0.727


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Showing 1 to 20 of 130 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_106935720 3.939 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2
chr6_+_34354119 3.482 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr17_+_29093763 3.283 ENSMUST00000023829.6
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_44617310 2.978 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr9_-_39604124 2.592 ENSMUST00000042485.4
ENSMUST00000141370.1
 AW551984

expressed sequence AW551984

chr3_+_102010138 2.002 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chrX_+_96455359 1.864 ENSMUST00000033553.7
 Heph
hephaestin
chr8_+_58912257 1.858 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr3_+_67892189 1.790 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr10_-_11082287 1.731 ENSMUST00000105561.2
ENSMUST00000044306.6
 Grm1

glutamate receptor, metabotropic 1

chr13_+_24614608 1.616 ENSMUST00000091694.3
 Fam65b
family with sequence similarity 65, member B
chr5_-_123666682 1.470 ENSMUST00000149410.1
 Clip1
CAP-GLY domain containing linker protein 1
chr11_-_69822144 1.392 ENSMUST00000045771.6
 Spem1
sperm maturation 1
chr11_-_78984831 1.267 ENSMUST00000073001.4
ENSMUST00000108269.3
 Lgals9

lectin, galactose binding, soluble 9

chr13_-_99516537 1.237 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr1_-_89933290 1.228 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr1_+_74713551 1.136 ENSMUST00000027356.5
 Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr4_-_119383732 1.109 ENSMUST00000044781.2
ENSMUST00000084307.3
 Ccdc30

coiled-coil domain containing 30

chr11_-_78984946 1.103 ENSMUST00000108268.3
 Lgals9
lectin, galactose binding, soluble 9
chr1_+_66321708 1.077 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 3.5 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.4 3.3 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.4 2.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.8 2.4 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 2.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 1.8 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 1.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 1.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.4 GO:0030317 sperm motility(GO:0030317)
0.2 1.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 1.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.3 1.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.2 1.7 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.5 1.6 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.1 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 0.6 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.2 GO:0033193 Lsd1/2 complex(GO:0033193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 3.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 2.4 GO:0016936 galactoside binding(GO:0016936)
0.3 2.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 1.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.7 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.2 1.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)