Motif ID: Sp2

Z-value: 0.532


Transcription factors associated with Sp2:

Gene SymbolEntrez IDGene Name
Sp2 ENSMUSG00000018678.6 Sp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp2mm10_v2_chr11_-_96968655_96968673-0.039.0e-01Click!


Activity profile for motif Sp2.

activity profile for motif Sp2


Sorted Z-values histogram for motif Sp2

Sorted Z-values for motif Sp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 2.414 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr11_-_63922257 0.888 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_184033998 0.831 ENSMUST00000050306.5
 1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr4_-_68954351 0.755 ENSMUST00000030036.5
 Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr2_-_35336969 0.603 ENSMUST00000028241.6
 Stom
stomatin
chr7_-_110061319 0.595 ENSMUST00000098110.2
 AA474408
expressed sequence AA474408
chr1_+_184034381 0.574 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chr7_-_17062384 0.572 ENSMUST00000153833.1
ENSMUST00000108492.2
 Hif3a

hypoxia inducible factor 3, alpha subunit

chr2_+_164960809 0.568 ENSMUST00000124372.1
 Slc12a5
solute carrier family 12, member 5
chr1_+_72824482 0.564 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr9_-_20976762 0.504 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr2_-_26246707 0.500 ENSMUST00000166349.1
 C030048H21Rik
RIKEN cDNA C030048H21 gene
chr4_-_117133953 0.483 ENSMUST00000076859.5
 Plk3
polo-like kinase 3
chrX_-_133688978 0.480 ENSMUST00000149154.1
ENSMUST00000167944.1
 Pcdh19

protocadherin 19

chr1_-_144004142 0.459 ENSMUST00000127206.1
 Rgs2
regulator of G-protein signaling 2
chr19_-_23652780 0.456 ENSMUST00000035849.3
 1700028P14Rik
RIKEN cDNA 1700028P14 gene
chr14_-_122983211 0.440 ENSMUST00000037726.7
 Tmtc4
transmembrane and tetratricopeptide repeat containing 4
chr12_+_112678803 0.437 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
 Zbtb42


zinc finger and BTB domain containing 42


chr8_-_57653023 0.435 ENSMUST00000034021.5
 Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr12_+_41024329 0.424 ENSMUST00000134965.1
 Immp2l
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.9 GO:0006477 protein sulfation(GO:0006477)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.8 GO:0042711 maternal behavior(GO:0042711)
0.1 0.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.1 0.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.2 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.5 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.5 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.5 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.4 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0090537 CERF complex(GO:0090537)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.4 GO:0019841 retinol binding(GO:0019841)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)