Motif ID: Esrrg

Z-value: 0.304


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187997821_187997834-0.602.5e-03Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 188 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_68869563 1.019 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr9_-_107668967 1.018 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr17_-_81649607 0.792 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr10_+_79716588 0.737 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr1_+_104768510 0.651 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr7_-_105482197 0.644 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr18_+_45268876 0.575 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr3_-_107517321 0.515 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr7_-_37772868 0.479 ENSMUST00000176205.1
 Zfp536
zinc finger protein 536
chr19_+_6400611 0.460 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr7_-_93081027 0.430 ENSMUST00000098303.1
 Gm9934
predicted gene 9934
chr19_+_6400523 0.421 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr19_+_6399857 0.415 ENSMUST00000146601.1
ENSMUST00000150713.1
 Rasgrp2

RAS, guanyl releasing protein 2

chr4_-_82505707 0.403 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr11_-_97573929 0.390 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1

chr3_+_90514435 0.379 ENSMUST00000048138.6
ENSMUST00000181271.1
 S100a13

S100 calcium binding protein A13

chr2_+_164785823 0.375 ENSMUST00000174070.1
ENSMUST00000172577.1
ENSMUST00000056181.6
 Snx21


sorting nexin family member 21


chr3_-_90514250 0.364 ENSMUST00000107340.1
ENSMUST00000060738.8
 S100a1

S100 calcium binding protein A1

chr19_-_43674844 0.349 ENSMUST00000046038.7
 Slc25a28
solute carrier family 25, member 28
chr1_+_75546522 0.342 ENSMUST00000138814.1
 Slc4a3
solute carrier family 4 (anion exchanger), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.0 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.2 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.7 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.6 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.1 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.8 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)