Motif ID: Bcl6

Z-value: 0.646


Transcription factors associated with Bcl6:

Gene SymbolEntrez IDGene Name
Bcl6 ENSMUSG00000022508.5 Bcl6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6mm10_v2_chr16_-_23988852_239888520.387.0e-02Click!


Activity profile for motif Bcl6.

activity profile for motif Bcl6


Sorted Z-values histogram for motif Bcl6

Sorted Z-values for motif Bcl6



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6

PNG image of the network

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Top targets:


Showing 1 to 20 of 192 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_101245996 1.872 ENSMUST00000129680.1
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_-_55419898 1.716 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr10_+_58813359 1.379 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr4_+_144892813 1.303 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr3_-_80802789 1.274 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_-_64046925 1.213 ENSMUST00000107377.3
 Tnc
tenascin C
chr15_-_8710734 1.199 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_78499087 1.198 ENSMUST00000017488.4
 Vtn
vitronectin
chr16_-_5222257 1.172 ENSMUST00000050160.4
 AU021092
expressed sequence AU021092
chr11_-_48871408 1.057 ENSMUST00000097271.2
 Irgm1
immunity-related GTPase family M member 1
chr15_-_54919961 0.959 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr4_+_144893077 0.936 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_-_142661305 0.886 ENSMUST00000105936.1
 Igf2
insulin-like growth factor 2
chr9_+_20868628 0.858 ENSMUST00000043911.7
 A230050P20Rik
RIKEN cDNA A230050P20 gene
chr9_+_50752758 0.851 ENSMUST00000034562.7
 Cryab
crystallin, alpha B
chr15_-_37459327 0.848 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr15_-_54920115 0.790 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_-_8710409 0.766 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_37458523 0.762 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr17_-_45592569 0.757 ENSMUST00000163492.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.9 GO:0042572 retinol metabolic process(GO:0042572)
0.5 2.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 1.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 1.5 GO:0015862 uridine transport(GO:0015862)
0.3 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 1.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 1.2 GO:0097421 liver regeneration(GO:0097421)
0.0 1.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.9 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.7 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 0.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.6 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.6 GO:0035356 cellular triglyceride homeostasis(GO:0035356)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0043205 fibril(GO:0043205)
0.4 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.3 GO:0043195 terminal bouton(GO:0043195)
0.2 1.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0001652 granular component(GO:0001652)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 2.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.4 1.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.2 GO:0045545 syndecan binding(GO:0045545)
0.0 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)