Motif ID: Bcl6
Z-value: 0.646
Transcription factors associated with Bcl6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bcl6 | ENSMUSG00000022508.5 | Bcl6 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Bcl6 | mm10_v2_chr16_-_23988852_23988852 | 0.38 | 7.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.0 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.3 | 1.2 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.3 | 1.4 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
0.3 | 2.9 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.2 | 1.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.2 | 1.5 | GO:0015862 | uridine transport(GO:0015862) |
0.2 | 1.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.2 | 0.5 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
0.2 | 0.6 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
0.2 | 0.6 | GO:0033024 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
0.1 | 0.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.1 | 0.4 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.1 | 1.2 | GO:0097421 | liver regeneration(GO:0097421) |
0.1 | 0.5 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
0.1 | 0.6 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.1 | 0.9 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.4 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.1 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.1 | 0.3 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
0.1 | 0.3 | GO:0070366 | regulation of hepatocyte differentiation(GO:0070366) |
0.1 | 0.3 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.3 | GO:0042938 | dipeptide transport(GO:0042938) |
0.1 | 0.2 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.3 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.1 | 0.3 | GO:0048819 | regulation of hair follicle maturation(GO:0048819) regulation of catagen(GO:0051794) |
0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.1 | 0.3 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.1 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 1.3 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.2 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
0.0 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.0 | 1.7 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.0 | 0.3 | GO:0042730 | fibrinolysis(GO:0042730) |
0.0 | 0.2 | GO:2000587 | positive regulation of cell adhesion molecule production(GO:0060355) regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
0.0 | 0.9 | GO:0034340 | response to type I interferon(GO:0034340) |
0.0 | 0.6 | GO:0007614 | short-term memory(GO:0007614) |
0.0 | 0.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.2 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.0 | 0.1 | GO:0019236 | response to pheromone(GO:0019236) |
0.0 | 0.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.3 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.0 | 0.1 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
0.0 | 0.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 1.0 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.0 | 0.5 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.0 | 0.7 | GO:1904030 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.2 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 1.4 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.0 | 0.3 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
0.0 | 0.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 0.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.4 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
0.0 | 0.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
0.0 | 0.2 | GO:1902287 | semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
0.0 | 0.4 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.0 | 0.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.1 | GO:0071494 | cellular response to UV-C(GO:0071494) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.3 | 0.9 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.2 | 1.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.1 | 2.0 | GO:0043205 | fibril(GO:0043205) |
0.1 | 0.6 | GO:0001652 | granular component(GO:0001652) |
0.1 | 1.7 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 0.2 | GO:0097447 | dendritic tree(GO:0097447) |
0.1 | 1.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.1 | 0.4 | GO:0042627 | chylomicron(GO:0042627) |
0.1 | 0.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.2 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.0 | 0.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 1.3 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.1 | GO:0005915 | zonula adherens(GO:0005915) |
0.0 | 0.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.7 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
0.4 | 2.9 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.4 | 2.0 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.2 | 1.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.2 | 0.6 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.2 | 1.2 | GO:0045545 | syndecan binding(GO:0045545) |
0.2 | 1.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.1 | 0.5 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
0.1 | 0.3 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.1 | 0.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.1 | 1.5 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 0.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.6 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.1 | 0.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 1.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.1 | 0.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.1 | 0.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.1 | 0.3 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.1 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.0 | 1.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 1.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.4 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
0.0 | 0.7 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.3 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.0 | 1.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.4 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.2 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 0.2 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.2 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.2 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.1 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |