Motif ID: Nr2c2

Z-value: 0.733


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92091378_92091390-0.369.4e-02Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_99695809 1.089 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chr15_+_3270767 0.820 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_+_79500018 0.786 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr10_-_79984227 0.770 ENSMUST00000052885.7
 Tmem259
transmembrane protein 259
chr3_+_121967822 0.763 ENSMUST00000137089.1
 Arhgap29
Rho GTPase activating protein 29
chr10_-_79983970 0.740 ENSMUST00000124536.1
 Tmem259
transmembrane protein 259
chr4_-_139092958 0.667 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr19_+_46707443 0.638 ENSMUST00000003655.7
 As3mt
arsenic (+3 oxidation state) methyltransferase
chr16_-_4624984 0.634 ENSMUST00000014445.6
 Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr7_+_98494222 0.628 ENSMUST00000165205.1
 Lrrc32
leucine rich repeat containing 32
chr1_+_171329376 0.597 ENSMUST00000111299.1
ENSMUST00000064950.4
 Dedd

death effector domain-containing

chr17_-_56717681 0.570 ENSMUST00000164907.1
 Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr9_-_124424154 0.561 ENSMUST00000180270.1
 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr7_+_79500081 0.539 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr1_-_120120138 0.509 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr17_+_47695171 0.496 ENSMUST00000113296.1
 Frs3
fibroblast growth factor receptor substrate 3
chr8_+_88521344 0.493 ENSMUST00000034086.5
 Nkd1
naked cuticle 1 homolog (Drosophila)
chr6_+_124663027 0.462 ENSMUST00000004381.7
 Lpcat3
lysophosphatidylcholine acyltransferase 3
chr6_-_88875035 0.459 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr17_+_56717759 0.457 ENSMUST00000002452.6
 Ndufa11
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 167 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 1.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.8 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 0.7 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.7 GO:0030421 defecation(GO:0030421)
0.1 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.7 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.2 0.6 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.1 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0060028 convergent extension involved in axis elongation(GO:0060028)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.7 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.6 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.6 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.2 0.7 GO:0016015 morphogen activity(GO:0016015)
0.2 0.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0047631 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)