Motif ID: Mafb

Z-value: 0.696


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.574.5e-03Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_130936172 2.856 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr7_-_120202104 2.552 ENSMUST00000033198.5
 Crym
crystallin, mu
chr4_-_136886187 2.021 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr18_+_65873478 1.964 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr7_-_141010759 1.458 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr8_+_25532125 1.441 ENSMUST00000167764.1
 Fgfr1
fibroblast growth factor receptor 1
chr2_+_170731807 1.297 ENSMUST00000029075.4
 Dok5
docking protein 5
chr10_+_127705170 1.295 ENSMUST00000079590.5
 Myo1a
myosin IA
chr2_+_22622183 1.259 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr3_+_94398517 1.196 ENSMUST00000050975.3
 Lingo4
leucine rich repeat and Ig domain containing 4
chr17_+_22689771 1.188 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr14_+_80000292 1.172 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr7_-_46672537 1.123 ENSMUST00000049298.7
 Tph1
tryptophan hydroxylase 1
chr6_+_120773633 1.107 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr8_+_70172383 1.081 ENSMUST00000002413.8
ENSMUST00000182980.1
ENSMUST00000182365.1
 Tmem161a


transmembrane protein 161A


chr17_+_3532554 1.075 ENSMUST00000168560.1
 Cldn20
claudin 20
chr7_+_140941550 1.002 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr2_-_130397525 0.973 ENSMUST00000028897.7
 Cpxm1
carboxypeptidase X 1 (M14 family)
chr10_-_42276688 0.943 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr4_-_41124292 0.923 ENSMUST00000030138.8
 Nol6
nucleolar protein family 6 (RNA-associated)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.5 2.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 2.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 1.7 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 1.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.5 1.4 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.3 1.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 1.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 1.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 1.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 1.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 1.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.3 0.9 GO:0051031 tRNA transport(GO:0051031)
0.1 0.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0005770 late endosome(GO:0005770)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.2 GO:0042581 specific granule(GO:0042581)
0.1 1.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 0.5 GO:0045160 myosin I complex(GO:0045160)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 2.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 1.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.0 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1 0.9 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 0.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)