Motif ID: Zfp105

Z-value: 0.599


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.359.9e-02Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144892813 5.108 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_+_17574268 3.085 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_84773381 2.399 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_128359065 2.317 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr5_+_13399309 2.152 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr1_-_190170671 2.037 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr8_-_11008458 1.588 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr18_+_69344503 1.458 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr5_-_111761697 1.426 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr12_-_90738438 1.168 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr13_-_67609617 1.091 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr4_+_11704439 1.074 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr13_-_67609667 1.045 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr2_-_177267036 0.932 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr2_-_91931774 0.899 ENSMUST00000069423.6
 Mdk
midkine
chr11_-_100411874 0.713 ENSMUST00000141840.1
 Leprel4
leprecan-like 4
chr8_-_64205970 0.529 ENSMUST00000066166.4
 Tll1
tolloid-like
chr1_-_13589717 0.525 ENSMUST00000027068.4
 Tram1
translocating chain-associating membrane protein 1
chr5_+_19907502 0.520 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_37484955 0.489 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr18_+_30272747 0.392 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3


chr11_+_108920342 0.385 ENSMUST00000052915.7
 Axin2
axin2
chr2_+_107290590 0.360 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chrM_+_3906 0.288 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr14_+_31019159 0.286 ENSMUST00000112094.1
ENSMUST00000144009.1
 Pbrm1

polybromo 1

chr7_-_34313531 0.235 ENSMUST00000108074.1
 4931406P16Rik
RIKEN cDNA 4931406P16 gene
chr10_+_128267997 0.219 ENSMUST00000050901.2
 Apof
apolipoprotein F
chr17_+_6079928 0.205 ENSMUST00000100955.2
 Gtf2h5
general transcription factor IIH, polypeptide 5
chr6_-_127151044 0.203 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr7_+_66109474 0.172 ENSMUST00000036372.6
 Chsy1
chondroitin sulfate synthase 1
chr8_+_20136455 0.159 ENSMUST00000179299.1
ENSMUST00000096485.4
 Gm21811

predicted gene, 21811

chr14_-_36968679 0.158 ENSMUST00000067700.6
 Ccser2
coiled-coil serine rich 2
chr6_-_142964404 0.148 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_+_108920800 0.141 ENSMUST00000140821.1
 Axin2
axin2
chr1_+_179960472 0.131 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr18_+_35770318 0.126 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr8_+_20567716 0.099 ENSMUST00000178995.1
 Gm21092
predicted gene, 21092
chr1_-_63114516 0.083 ENSMUST00000097718.2
 Ino80d
INO80 complex subunit D
chr9_+_78175898 0.081 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr15_+_85510812 0.059 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr11_-_102316691 0.006 ENSMUST00000107115.1
ENSMUST00000128016.1
 Ubtf

upstream binding transcription factor, RNA polymerase I


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.7 2.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 5.1 GO:0042572 retinol metabolic process(GO:0042572)
0.3 0.9 GO:0030421 defecation(GO:0030421)
0.2 1.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.2 2.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 1.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.3 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 0.5 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 1.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 5.2 GO:0038191 neuropilin binding(GO:0038191)
0.5 2.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 2.0 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)