Motif ID: Nfatc4

Z-value: 0.391


Transcription factors associated with Nfatc4:

Gene SymbolEntrez IDGene Name
Nfatc4 ENSMUSG00000023411.5 Nfatc4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc4mm10_v2_chr14_+_55824795_55824889-0.462.7e-02Click!


Activity profile for motif Nfatc4.

activity profile for motif Nfatc4


Sorted Z-values histogram for motif Nfatc4

Sorted Z-values for motif Nfatc4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc4

PNG image of the network

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Top targets:


Showing 1 to 20 of 58 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.294 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr13_+_83504032 1.120 ENSMUST00000163888.1
ENSMUST00000005722.7
 Mef2c

myocyte enhancer factor 2C

chr18_-_62741387 0.819 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr3_-_37125943 0.804 ENSMUST00000029275.5
 Il2
interleukin 2
chr11_+_97415527 0.791 ENSMUST00000121799.1
 Arhgap23
Rho GTPase activating protein 23
chr1_-_193370225 0.650 ENSMUST00000169907.1
 Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr1_-_193370260 0.640 ENSMUST00000016323.4
 Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr13_-_52981027 0.566 ENSMUST00000071065.7
 Nfil3
nuclear factor, interleukin 3, regulated
chr15_+_92051153 0.557 ENSMUST00000169825.1
 Cntn1
contactin 1
chr19_-_8839181 0.458 ENSMUST00000096259.4
 Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr13_+_51846673 0.367 ENSMUST00000021903.2
 Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_70849644 0.348 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
 Tgif1


TGFB-induced factor homeobox 1


chr2_+_55435918 0.347 ENSMUST00000067101.3
 Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr6_-_59024470 0.333 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A
chr1_-_126830632 0.329 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr2_+_125136692 0.323 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr17_-_70851710 0.291 ENSMUST00000166395.2
 Tgif1
TGFB-induced factor homeobox 1
chr6_-_59024340 0.287 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr10_+_4611971 0.275 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr19_-_4943049 0.264 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
 Peli3


pellino 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.1 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 0.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 0.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.4 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 0.3 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0070051 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132) fibrinogen binding(GO:0070051)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)