Motif ID: Tfap2b

Z-value: 1.001


Transcription factors associated with Tfap2b:

Gene SymbolEntrez IDGene Name
Tfap2b ENSMUSG00000025927.7 Tfap2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2bmm10_v2_chr1_+_19212054_19212106-0.846.4e-07Click!


Activity profile for motif Tfap2b.

activity profile for motif Tfap2b


Sorted Z-values histogram for motif Tfap2b

Sorted Z-values for motif Tfap2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_48045144 6.769 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr12_+_70825492 6.208 ENSMUST00000057859.7
 Frmd6
FERM domain containing 6
chr19_+_5740885 6.036 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr1_-_56978534 5.699 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr2_+_91945703 3.902 ENSMUST00000178895.1
 Gm9821
predicted gene 9821
chr12_+_84009481 3.706 ENSMUST00000168120.1
 Acot1
acyl-CoA thioesterase 1
chr1_-_56972437 3.675 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr9_-_40455670 3.673 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr17_+_83215271 3.392 ENSMUST00000170794.1
 Pkdcc
protein kinase domain containing, cytoplasmic
chr11_+_35121126 3.056 ENSMUST00000069837.3
 Slit3
slit homolog 3 (Drosophila)
chr6_-_37299950 2.623 ENSMUST00000101532.3
 Dgki
diacylglycerol kinase, iota
chr8_+_84723003 2.593 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr10_+_13966268 2.488 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr13_+_49187485 2.400 ENSMUST00000049022.8
ENSMUST00000120733.1
 Ninj1

ninjurin 1

chr7_+_78578830 2.151 ENSMUST00000064591.4
 Gm9885
predicted gene 9885
chr1_-_14310198 2.123 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr12_-_76709997 2.050 ENSMUST00000166101.1
 Sptb
spectrin beta, erythrocytic
chr4_-_22488296 2.038 ENSMUST00000178174.1
 Pou3f2
POU domain, class 3, transcription factor 2
chr2_+_153031852 1.912 ENSMUST00000037235.6
 Xkr7
X Kell blood group precursor related family member 7 homolog
chr18_+_64340225 1.780 ENSMUST00000175965.2
ENSMUST00000115145.3
 Onecut2

one cut domain, family member 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 9.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.3 6.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.0 6.2 GO:0003383 apical constriction(GO:0003383)
2.0 6.0 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 4.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.7 3.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.3 3.3 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 3.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.5 3.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 2.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.9 2.6 GO:0046959 habituation(GO:0046959)
0.5 2.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.2 2.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 2.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 2.1 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.5 2.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 2.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 1.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 9.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 5.9 GO:0043296 apical junction complex(GO:0043296)
0.2 3.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.1 GO:0001726 ruffle(GO:0001726)
0.3 2.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 2.2 GO:0008091 spectrin(GO:0008091)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0030139 endocytic vesicle(GO:0030139)
0.2 1.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 5.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 3.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 3.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.4 3.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.4 2.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.5 GO:0005522 profilin binding(GO:0005522)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.2 2.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 2.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 1.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.5 1.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.4 GO:0005042 netrin receptor activity(GO:0005042)