Motif ID: Gata5

Z-value: 0.742


Transcription factors associated with Gata5:

Gene SymbolEntrez IDGene Name
Gata5 ENSMUSG00000015627.5 Gata5



Activity profile for motif Gata5.

activity profile for motif Gata5


Sorted Z-values histogram for motif Gata5

Sorted Z-values for motif Gata5



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata5

PNG image of the network

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Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 5.540 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276400 3.551 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 3.525 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr14_+_75455957 2.562 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr10_-_26078987 2.513 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr16_-_44558879 2.178 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr7_-_70366735 1.596 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr13_+_108316332 1.500 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr8_+_45658666 1.380 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_+_108316395 1.094 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr8_+_45658273 1.084 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr5_+_93093428 1.083 ENSMUST00000074733.7
Sept11
septin 11
chr12_+_95692212 1.072 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr6_-_119330668 1.052 ENSMUST00000112756.1
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr6_-_119330723 1.046 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr8_+_67494843 0.990 ENSMUST00000093470.5
ENSMUST00000163856.1
Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

chr11_+_95337012 0.911 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr6_-_92706145 0.896 ENSMUST00000032093.5
Prickle2
prickle homolog 2 (Drosophila)
chr16_-_34095983 0.895 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr14_+_70457447 0.894 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 12.6 GO:0015671 oxygen transport(GO:0015671)
0.1 2.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5 2.6 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 2.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.3 1.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 1.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 0.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.9 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.5 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.4 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 2.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 12.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)