Motif ID: Zfp423

Z-value: 0.526


Transcription factors associated with Zfp423:

Gene SymbolEntrez IDGene Name
Zfp423 ENSMUSG00000045333.9 Zfp423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp423mm10_v2_chr8_-_87804411_878044630.272.2e-01Click!


Activity profile for motif Zfp423.

activity profile for motif Zfp423


Sorted Z-values histogram for motif Zfp423

Sorted Z-values for motif Zfp423



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp423

PNG image of the network

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Top targets:


Showing 1 to 20 of 82 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_54902743 1.076 ENSMUST00000082430.3
 Gpx3
glutathione peroxidase 3
chr11_+_54902917 0.928 ENSMUST00000149324.1
 Gpx3
glutathione peroxidase 3
chr9_-_37552904 0.902 ENSMUST00000065668.5
 Nrgn
neurogranin
chrX_+_7822289 0.861 ENSMUST00000009875.4
 Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr2_+_180499893 0.817 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr8_+_58912257 0.789 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr12_+_109459843 0.735 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr6_+_110645572 0.701 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr4_+_42917234 0.607 ENSMUST00000107976.2
ENSMUST00000069184.2
 N28178

expressed sequence N28178

chr1_+_167598450 0.602 ENSMUST00000111386.1
ENSMUST00000111384.1
 Rxrg

retinoid X receptor gamma

chr6_+_86628174 0.528 ENSMUST00000043400.6
 Asprv1
aspartic peptidase, retroviral-like 1
chr19_+_6401675 0.515 ENSMUST00000113471.1
ENSMUST00000113469.2
 Rasgrp2

RAS, guanyl releasing protein 2

chr7_+_29307924 0.469 ENSMUST00000108230.1
ENSMUST00000065181.5
 Dpf1

D4, zinc and double PHD fingers family 1

chr19_+_10041548 0.450 ENSMUST00000115995.2
 Fads3
fatty acid desaturase 3
chr6_+_6863769 0.448 ENSMUST00000031768.6
 Dlx6
distal-less homeobox 6
chr8_+_27260327 0.446 ENSMUST00000033880.5
 Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr17_-_10840285 0.437 ENSMUST00000041463.6
 Pacrg
PARK2 co-regulated
chr16_+_17489639 0.417 ENSMUST00000023448.6
 Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr2_-_147085445 0.404 ENSMUST00000067020.2
 Nkx2-4
NK2 homeobox 4
chr10_-_62110945 0.395 ENSMUST00000142821.1
ENSMUST00000124615.1
ENSMUST00000064050.4
ENSMUST00000125704.1
ENSMUST00000142796.1
 2010107G23Rik




RIKEN cDNA 2010107G23 gene





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.9 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 0.8 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.1 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.2 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0008430 selenium binding(GO:0008430)
0.2 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 0.7 GO:0070905 serine binding(GO:0070905)
0.1 0.5 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.2 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0050827 toxin receptor binding(GO:0050827)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)