Motif ID: Hnf1a

Z-value: 0.504


Transcription factors associated with Hnf1a:

Gene SymbolEntrez IDGene Name
Hnf1a ENSMUSG00000029556.6 Hnf1a



Activity profile for motif Hnf1a.

activity profile for motif Hnf1a


Sorted Z-values histogram for motif Hnf1a

Sorted Z-values for motif Hnf1a



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_70630149 1.294 ENSMUST00000022694.9
 Dmtn
dematin actin binding protein
chr9_+_53771499 1.035 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr19_-_14598031 0.953 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 0.841 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr13_-_53286052 0.748 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr8_-_95142477 0.689 ENSMUST00000034240.7
ENSMUST00000169748.1
 Kifc3

kinesin family member C3

chr1_+_133309778 0.652 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
 Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr18_+_33464163 0.631 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr17_-_35132050 0.562 ENSMUST00000025249.6
 Apom
apolipoprotein M
chr5_+_8046077 0.507 ENSMUST00000088786.4
 Sri
sorcin
chrX_-_43167817 0.488 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr1_+_125676969 0.475 ENSMUST00000027581.6
 Gpr39
G protein-coupled receptor 39
chr13_+_55152640 0.472 ENSMUST00000005452.5
 Fgfr4
fibroblast growth factor receptor 4
chr7_+_141216626 0.452 ENSMUST00000141804.1
ENSMUST00000148975.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr11_+_118428203 0.352 ENSMUST00000124861.1
 C1qtnf1
C1q and tumor necrosis factor related protein 1
chr7_+_141215852 0.326 ENSMUST00000046890.5
ENSMUST00000133763.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr9_-_106158109 0.318 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr11_-_98022594 0.313 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
 Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr17_+_71204647 0.298 ENSMUST00000126681.1
 Lpin2
lipin 2
chr7_-_45062393 0.298 ENSMUST00000129101.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr16_+_20591156 0.259 ENSMUST00000159780.1
 Vwa5b2
von Willebrand factor A domain containing 5B2
chr11_+_3983704 0.259 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_3983636 0.226 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr19_+_6105774 0.209 ENSMUST00000044451.3
 Naaladl1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr11_+_78178105 0.195 ENSMUST00000147819.1
 Tlcd1
TLC domain containing 1
chr16_-_52296924 0.171 ENSMUST00000167115.1
 Alcam
activated leukocyte cell adhesion molecule
chr14_-_36919314 0.167 ENSMUST00000182797.1
 Ccser2
coiled-coil serine rich 2
chr15_-_79285502 0.154 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr5_+_122391878 0.148 ENSMUST00000102525.4
 Arpc3
actin related protein 2/3 complex, subunit 3
chr4_-_97778042 0.145 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_11898092 0.140 ENSMUST00000178704.1
 Ddc
dopa decarboxylase
chr16_+_20651652 0.140 ENSMUST00000007212.8
 Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr11_-_11898044 0.139 ENSMUST00000066237.3
 Ddc
dopa decarboxylase
chr4_+_150853919 0.135 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr2_-_86347764 0.124 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr18_-_33463747 0.119 ENSMUST00000171533.1
 Nrep
neuronal regeneration related protein
chr14_-_36919513 0.118 ENSMUST00000182042.1
 Ccser2
coiled-coil serine rich 2
chr6_-_137571007 0.115 ENSMUST00000100841.2
 Eps8
epidermal growth factor receptor pathway substrate 8
chr12_+_5411641 0.111 ENSMUST00000163627.1
 2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr9_+_99629823 0.098 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr9_-_71163224 0.093 ENSMUST00000074465.2
 Aqp9
aquaporin 9
chr10_+_87859255 0.089 ENSMUST00000105300.2
 Igf1
insulin-like growth factor 1
chr2_-_32424005 0.083 ENSMUST00000113307.2
 Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr7_+_45062429 0.074 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
 Nosip



nitric oxide synthase interacting protein



chr7_-_144751968 0.073 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr19_+_42045792 0.064 ENSMUST00000172244.1
ENSMUST00000081714.4
 Hoga1

4-hydroxy-2-oxoglutarate aldolase 1

chr8_+_64947177 0.062 ENSMUST00000079896.7
ENSMUST00000026595.5
 Tmem192

transmembrane protein 192

chr18_-_33464007 0.045 ENSMUST00000168890.1
 Nrep
neuronal regeneration related protein
chr19_-_30549516 0.043 ENSMUST00000025803.8
 Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr10_+_87859062 0.038 ENSMUST00000095360.4
 Igf1
insulin-like growth factor 1
chr18_-_6516089 0.037 ENSMUST00000115870.2
 Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr7_+_140763739 0.037 ENSMUST00000026552.7
 Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr6_+_29859662 0.029 ENSMUST00000128927.2
 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_+_29859686 0.028 ENSMUST00000134438.1
 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr3_+_136670076 0.026 ENSMUST00000070198.7
 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_-_155357392 0.015 ENSMUST00000165234.1
ENSMUST00000077626.6
 Pigu

phosphatidylinositol glycan anchor biosynthesis, class U

chr9_+_57827284 0.008 ENSMUST00000163186.1
 Gm17231
predicted gene 17231
chr2_-_68472138 0.002 ENSMUST00000102715.3
 Stk39
serine/threonine kinase 39

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.2 0.7 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.2 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 0.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 0.6 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.1 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) motor learning(GO:0061743) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)