Motif ID: Gcm1

Z-value: 0.477


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.252.4e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 63 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_101246960 1.679 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr12_-_119238794 1.449 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chrX_+_73503074 1.114 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr2_-_180225812 0.932 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr4_-_136956784 0.905 ENSMUST00000030420.8
 Epha8
Eph receptor A8
chr11_-_6065538 0.820 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr18_-_39487096 0.764 ENSMUST00000097592.2
ENSMUST00000115571.1
 Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr19_+_6400523 0.735 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr2_+_128126030 0.721 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
 Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr7_-_99182681 0.701 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr15_-_10470490 0.631 ENSMUST00000136591.1
 Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr13_-_95250166 0.549 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
 Pde8b



phosphodiesterase 8B



chr7_+_46396439 0.504 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr16_-_91597636 0.488 ENSMUST00000023686.8
 Tmem50b
transmembrane protein 50B
chr19_+_6400611 0.476 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr5_-_35105691 0.421 ENSMUST00000030986.8
 Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr19_+_46761578 0.360 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr12_+_8674224 0.297 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr7_+_119900099 0.296 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr16_-_36874806 0.289 ENSMUST00000075946.5
 Eaf2
ELL associated factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.3 0.8 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.2 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.7 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 0.5 GO:0035106 operant conditioning(GO:0035106)
0.1 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.5 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 0.4 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 0.9 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0045502 dynein binding(GO:0045502)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.2 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)