Motif ID: Gcm1

Z-value: 0.477


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.252.4e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_101246960 1.679 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr12_-_119238794 1.449 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chrX_+_73503074 1.114 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr2_-_180225812 0.932 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr4_-_136956784 0.905 ENSMUST00000030420.8
 Epha8
Eph receptor A8
chr11_-_6065538 0.820 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr18_-_39487096 0.764 ENSMUST00000097592.2
ENSMUST00000115571.1
 Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr19_+_6400523 0.735 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr2_+_128126030 0.721 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
 Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr7_-_99182681 0.701 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr15_-_10470490 0.631 ENSMUST00000136591.1
 Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr13_-_95250166 0.549 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
 Pde8b



phosphodiesterase 8B



chr7_+_46396439 0.504 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr16_-_91597636 0.488 ENSMUST00000023686.8
 Tmem50b
transmembrane protein 50B
chr19_+_6400611 0.476 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr5_-_35105691 0.421 ENSMUST00000030986.8
 Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr19_+_46761578 0.360 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr12_+_8674224 0.297 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr7_+_119900099 0.296 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr16_-_36874806 0.289 ENSMUST00000075946.5
 Eaf2
ELL associated factor 2
chr11_-_75454656 0.278 ENSMUST00000173320.1
 Wdr81
WD repeat domain 81
chr11_-_60352869 0.247 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
 Tom1l2





target of myb1-like 2 (chicken)





chr17_+_8311101 0.245 ENSMUST00000154553.1
 Sft2d1
SFT2 domain containing 1
chr16_-_3907651 0.226 ENSMUST00000177221.1
ENSMUST00000177323.1
 1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr2_+_105904629 0.222 ENSMUST00000037499.5
 Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_23679363 0.218 ENSMUST00000024699.2
 Cldn6
claudin 6
chr2_+_96318014 0.215 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chr12_+_8674129 0.209 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr16_+_36875119 0.209 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr17_+_24696234 0.203 ENSMUST00000019464.7
 Noxo1
NADPH oxidase organizer 1
chr8_+_91070052 0.198 ENSMUST00000034091.7
 Rbl2
retinoblastoma-like 2
chr1_+_53313636 0.198 ENSMUST00000114484.1
 Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr1_+_53313622 0.192 ENSMUST00000027265.3
 Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr17_+_25471564 0.180 ENSMUST00000025002.1
 Tekt4
tektin 4
chr8_+_105170668 0.176 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
 Cbfb



core binding factor beta



chr4_-_42661893 0.169 ENSMUST00000108006.3
 Il11ra2
interleukin 11 receptor, alpha chain 2
chr11_-_106613370 0.165 ENSMUST00000128933.1
 Tex2
testis expressed gene 2
chr6_+_6863769 0.161 ENSMUST00000031768.6
 Dlx6
distal-less homeobox 6
chr14_-_66213552 0.156 ENSMUST00000178730.1
 Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr1_+_43092588 0.155 ENSMUST00000039080.3
 8430432A02Rik
RIKEN cDNA 8430432A02 gene
chr1_-_79761752 0.131 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
 Wdfy1






WD repeat and FYVE domain containing 1






chr13_+_8202922 0.126 ENSMUST00000123187.1
 Adarb2
adenosine deaminase, RNA-specific, B2
chr2_-_39226343 0.121 ENSMUST00000028087.3
 Ppp6c
protein phosphatase 6, catalytic subunit
chr13_+_8202885 0.116 ENSMUST00000139438.1
ENSMUST00000135574.1
 Adarb2

adenosine deaminase, RNA-specific, B2

chr7_-_29906524 0.105 ENSMUST00000159920.1
ENSMUST00000162592.1
 Zfp27

zinc finger protein 27

chrX_+_93286499 0.101 ENSMUST00000046565.7
ENSMUST00000113947.2
 Arx

aristaless related homeobox

chr4_-_156234777 0.096 ENSMUST00000105569.3
 Klhl17
kelch-like 17
chr17_-_24696147 0.094 ENSMUST00000046839.8
 Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr16_+_38902305 0.076 ENSMUST00000023478.7
 Igsf11
immunoglobulin superfamily, member 11
chr13_+_8202860 0.074 ENSMUST00000064473.6
 Adarb2
adenosine deaminase, RNA-specific, B2
chr14_+_55578360 0.073 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
 Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr5_-_110343009 0.072 ENSMUST00000058016.9
ENSMUST00000112478.3
 P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr15_+_79348061 0.069 ENSMUST00000163691.1
 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr14_-_32201869 0.067 ENSMUST00000170331.1
ENSMUST00000013845.6
 Timm23

translocase of inner mitochondrial membrane 23

chr11_-_98149551 0.057 ENSMUST00000103143.3
 Fbxl20
F-box and leucine-rich repeat protein 20
chr11_-_121354337 0.056 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
 Wdr45b


WD repeat domain 45B


chrX_+_7657260 0.055 ENSMUST00000033485.7
 Prickle3
prickle homolog 3 (Drosophila)
chr10_-_76345254 0.035 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
 Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr13_+_100108155 0.027 ENSMUST00000129014.1
 Serf1
small EDRK-rich factor 1
chrX_-_75130914 0.025 ENSMUST00000114091.1
 Mpp1
membrane protein, palmitoylated
chr2_-_105904484 0.022 ENSMUST00000122965.1
 Elp4
elongation protein 4 homolog (S. cerevisiae)
chr9_-_70657121 0.017 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr3_-_69598822 0.011 ENSMUST00000061826.1
 B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.2 0.5 GO:0035106 operant conditioning(GO:0035106)
0.2 0.7 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.4 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.2 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.5 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 1.0 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)