Motif ID: Foxo6

Z-value: 0.362


Transcription factors associated with Foxo6:

Gene SymbolEntrez IDGene Name
Foxo6 ENSMUSG00000052135.8 Foxo6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_1202873490.203.5e-01Click!


Activity profile for motif Foxo6.

activity profile for motif Foxo6


Sorted Z-values histogram for motif Foxo6

Sorted Z-values for motif Foxo6



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_184883218 0.452 ENSMUST00000048308.5
 C130074G19Rik
RIKEN cDNA C130074G19 gene
chr10_-_93310963 0.436 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr6_+_88724667 0.388 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr4_+_102570065 0.380 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr10_-_93311073 0.377 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr8_+_25911670 0.362 ENSMUST00000120653.1
ENSMUST00000126226.1
 Kcnu1

potassium channel, subfamily U, member 1

chr15_+_3270767 0.328 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr16_+_10812915 0.320 ENSMUST00000115822.1
 Gm11172
predicted gene 11172
chr1_-_180245927 0.315 ENSMUST00000010753.7
 Psen2
presenilin 2
chr1_-_180245757 0.247 ENSMUST00000111104.1
 Psen2
presenilin 2
chr4_+_134510999 0.224 ENSMUST00000105866.2
 Aunip
aurora kinase A and ninein interacting protein
chr12_-_102423741 0.220 ENSMUST00000110020.1
 Lgmn
legumain
chr1_+_74391479 0.215 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr15_-_75111684 0.210 ENSMUST00000100542.3
 Ly6c2
lymphocyte antigen 6 complex, locus C2
chr7_+_143052739 0.196 ENSMUST00000037941.9
 Cd81
CD81 antigen
chr5_-_117389029 0.195 ENSMUST00000111953.1
ENSMUST00000086461.6
 Rfc5

replication factor C (activator 1) 5

chr2_-_84425258 0.189 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr18_-_60648290 0.170 ENSMUST00000143275.2
 Synpo
synaptopodin
chrX_+_134585644 0.168 ENSMUST00000113211.1
 Rpl36a
ribosomal protein L36A
chr2_-_155357392 0.164 ENSMUST00000165234.1
ENSMUST00000077626.6
 Pigu

phosphatidylinositol glycan anchor biosynthesis, class U

chr9_-_22071345 0.150 ENSMUST00000179605.1
ENSMUST00000043922.6
 Zfp653

zinc finger protein 653

chr2_+_120977017 0.141 ENSMUST00000067582.7
 Tmem62
transmembrane protein 62
chr4_-_139131058 0.137 ENSMUST00000143971.1
 Minos1
mitochondrial inner membrane organizing system 1
chr2_+_129593195 0.133 ENSMUST00000099113.3
ENSMUST00000103202.3
 Sirpa

signal-regulatory protein alpha

chr5_-_65391408 0.128 ENSMUST00000057885.6
 Rpl9
ribosomal protein L9
chr5_-_65391380 0.126 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
 Rpl9


ribosomal protein L9


chr14_+_34170640 0.125 ENSMUST00000104925.3
 Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chrX_-_163761323 0.124 ENSMUST00000059320.2
 Rnf138rt1
ring finger protein 138, retrogene 1
chr17_-_57839233 0.124 ENSMUST00000095218.3
 Rpl7a-ps5
ribosomal protein L7A, pseudogene 5
chr7_+_62476306 0.117 ENSMUST00000097132.3
 Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr11_+_85832551 0.114 ENSMUST00000000095.6
 Tbx2
T-box 2
chr5_+_110330697 0.112 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chr15_-_81843699 0.111 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr3_-_106167564 0.109 ENSMUST00000063062.8
 Chi3l3
chitinase 3-like 3
chr17_-_24696147 0.106 ENSMUST00000046839.8
 Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr8_+_36489191 0.104 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr1_+_171270321 0.100 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
 B4galt3


UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3


chr2_+_91650169 0.098 ENSMUST00000090614.4
 Arhgap1
Rho GTPase activating protein 1
chr5_+_115279666 0.095 ENSMUST00000040421.4
 Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr12_-_98577940 0.093 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr2_-_30194112 0.081 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr7_+_19368498 0.080 ENSMUST00000132655.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr3_-_51408925 0.079 ENSMUST00000038108.6
 Ndufc1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr2_+_4718145 0.078 ENSMUST00000056914.6
 Bend7
BEN domain containing 7
chr2_+_129592914 0.078 ENSMUST00000103203.1
 Sirpa
signal-regulatory protein alpha
chr10_+_79879614 0.078 ENSMUST00000006679.8
 Prtn3
proteinase 3
chr8_+_83566671 0.074 ENSMUST00000036996.5
 Ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr12_+_108410542 0.070 ENSMUST00000054955.7
 Eml1
echinoderm microtubule associated protein like 1
chr5_+_115605642 0.069 ENSMUST00000094427.3
 Gcn1l1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr7_+_140881898 0.067 ENSMUST00000026560.7
 Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr17_+_48346465 0.063 ENSMUST00000113237.3
 Trem2
triggering receptor expressed on myeloid cells 2
chr16_+_17146937 0.063 ENSMUST00000115706.1
ENSMUST00000069064.4
 Ydjc

YdjC homolog (bacterial)

chr15_+_103453782 0.059 ENSMUST00000047405.7
 Nckap1l
NCK associated protein 1 like
chr4_-_149099802 0.055 ENSMUST00000103217.4
 Pex14
peroxisomal biogenesis factor 14
chr2_-_75978164 0.055 ENSMUST00000099995.3
 Ttc30a2
tetratricopeptide repeat domain 30A2
chr15_+_52712434 0.055 ENSMUST00000037115.7
 Med30
mediator complex subunit 30
chr5_+_65391497 0.053 ENSMUST00000031101.3
ENSMUST00000122026.1
 Lias

lipoic acid synthetase

chrY_-_6681243 0.051 ENSMUST00000115940.1
 Gm21719
predicted gene, 21719
chr18_-_31911903 0.050 ENSMUST00000054984.6
 Sft2d3
SFT2 domain containing 3
chr4_+_62286441 0.049 ENSMUST00000084530.2
 Slc31a2
solute carrier family 31, member 2
chr14_-_50924626 0.049 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
 Osgep


O-sialoglycoprotein endopeptidase


chr5_+_7179299 0.046 ENSMUST00000179460.1
 Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr3_-_34351685 0.046 ENSMUST00000174114.1
 Gm20514
predicted gene 20514
chr12_+_108410625 0.044 ENSMUST00000109857.1
 Eml1
echinoderm microtubule associated protein like 1
chr7_+_28808795 0.044 ENSMUST00000172529.1
 Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr5_+_21186267 0.042 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr7_+_28440927 0.038 ENSMUST00000078845.6
 Gmfg
glia maturation factor, gamma
chr19_+_8892987 0.035 ENSMUST00000096249.5
 Ints5
integrator complex subunit 5
chr11_-_12027958 0.031 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr11_+_87853207 0.031 ENSMUST00000038196.6
 Mks1
Meckel syndrome, type 1
chrX_+_103493769 0.030 ENSMUST00000182447.1
ENSMUST00000182486.1
 Jpx

Jpx transcript, Xist activator (non-protein coding)

chr8_+_46986913 0.023 ENSMUST00000039840.7
ENSMUST00000119686.1
 Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

chr13_+_76579670 0.016 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr11_-_89639631 0.014 ENSMUST00000128717.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr1_+_51987139 0.011 ENSMUST00000168302.1
 Stat4
signal transducer and activator of transcription 4
chr12_-_113260217 0.011 ENSMUST00000178282.1
 Igha
immunoglobulin heavy constant alpha
chr6_+_57702601 0.006 ENSMUST00000072954.1
ENSMUST00000050077.8
 Lancl2

LanC (bacterial lantibiotic synthetase component C)-like 2

chr10_+_39420009 0.002 ENSMUST00000157009.1
 Fyn
Fyn proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.0 0.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.0 0.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0097421 liver regeneration(GO:0097421)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)